58567-80-9

Upstream product

• 98-51-1 4-tert-butyltoluene 
• 7252-86-0 4-tert-butylthioanisole 
• 920-39-8 isopropylmagnesium bromide 
• 118334-80-8 N-acyloxyphthalimide 
• 74-85-1 ethene 
• 120-12-7 anthracene 
• 75-66-1 2-methylpropan-2-thiol 
• 939-97-9 4-tert-Butylbenzaldehyde 
• 68175-34-8 1-(tert-butyl)-4-(prop-1-en-1-yl)benzene 
• 78-94-4 methyl vinyl ketone 
• 24475-36-3 4-[4-(1,1-dimethylethyl)phenyl]butanoic acid 
• 80-54-6 lilial 

Relevant academic research and scientific papers

Regioselective differentiation of vicinal methylene C-H bonds enabled by silver-catalysed nitrene transfer

Silver-catalyzed nitrene insertion enables the formation of benzosultams in good yield and with regioselectivity complementary to other transition metal nitrene-transfer catalysts. Preferential formation of six-membered benzosultam rings predominates for alkyl-substituted benzenesulphonamide precursors. Ligand-controlled tunability is also achieved for benzenesulphonamides with γ-branched alkyl substituents. Mechanistic probes suggest that the reaction pathway differs depending on whether a α (benzylic) or β (homobenzylic) C-H bond undergoes amidation, as well as the catalyst identity.

The Retro-Hydroformylation Reaction

Hydroformylation, a reaction that adds carbon monoxide and dihydrogen across an unsaturated carbon-carbon multiple bond, has been widely employed in the chemical industry since its discovery in 1938. In contrast, the reverse reaction, retro-hydroformylation, has seldom been studied. The retro-hydroformylation reaction of an aldehyde into an alkene and synthesis gas (a mixture of carbon monoxide and dihydrogen) in the presence of a cyclopentadienyl iridium catalyst is now reported. Aliphatic aldehydes were converted into the corresponding alkenes in up to 91 % yield with concomitant release of carbon monoxide and dihydrogen. Mechanistic control experiments indicated that the reaction proceeds by retro-hydroformylation and not by a sequential decarbonylation-dehydrogenation or dehydrogenation-decarbonylation process.

Reductive decarboxylation of N-(acyloxy)phthalimides via redox-initiated radical chain mechanism

Highly efficient reductive decarboxylation of N-(acyloxy)phthalimides which are readily prepared from carboxylic acids was achieved by visible light irradiation using Ru(bpy)3Cl2 as a sensitizer in the presence of BNAH and t-BuSH via radical chain mechanism.

PHOTODECARBOXYLATION OF UNMODIFIED CARBOXYLIC ACIDS WITH USE OF AZA AROMATIC COMPOUNDS

A very simple procedure for photodecarboxylation of intact carboxylic acids leading to alkanes is developed with use of aza aromatic compounds as light absorbers and t-BuSH as a hydrogen donor.

A General Olefin Synthesis

The reaction between secondary Grignard reagents and alkylthioarenes or alkylthioalkenes in the presence of 1:1 nickel dichloride-triphenylphosphine causing the substitution of alkylthio-groups by hydrogen atoms, the nickel(0)-induced replacement of alkylthio-groups of the aforementioned sulfides by alkyl or aryl functions, and the observation of regiocontrol in the catalysed reactions of Grignard reagents with unsymmetrical 1,1-bis(alkylthio)alkenes have led to a scheme of general, regio-, and stereo-selective olefin synthesis.