58584-26-2

Upstream product

• 763-32-6 2-methyl-1-buten-4-ol 
• 108-95-2 phenol 
• 80352-66-5 4-mesyloxy-2-methylbutene 
• 1458-98-6 2-methyl-3-bromo-1-propene 
• 6707-01-3 (chloromethoxy)benzene 

Downstream Products

• 14309-15-0 phenyl prenyl ether 
• 40614-27-5 4,4-dimethylchromane 
• 50585-12-1 (3-methyl-2-butenyl)cyclohexane 
• 107909-45-5 1-(3-methyl-3-buten-1-yl) oxy-4-(3-methyl-2-buten-1-yl)-benzene 
• 107909-42-2 1-phenoxy-3,7-dimethyl-6-octene-3-ol 
• 107909-44-4 1-(3-methyl-3-buten-1-yl) oxy-2-(3-methyl-2-buten-1-yl)-benzene 
• 87077-92-7 2-methyl-4-phenoxy-2-butanol 
• 1205638-98-7 (RS)-4-methyl-4-(2-phenoxy-ethyl)-4,5-dihydro-oxazol-2-ylamine 

Relevant academic research and scientific papers

Co-Catalyzed Hydroarylation of Unactivated Olefins

A mild, general, scalable, and functional group tolerant intramolecular hydroarylation of unactivated olefins using a Co(salen) complex, a N-fluoropyridinium salt, and a disiloxane reagent was reported. This method, which was carried out at room temperature, afforded six-membered benzocyclic compounds from mono-, 1,1- or trans-1,2-di, and trisubstituted olefins.

Achieving regio- and stereo-control in the fluorination of aziridines under acidic conditions

We developed an efficient fluorination protocol that converts easily accessible aziridines into β-fluoroamines, which are important motifs in biologically active molecules. In contrast with traditional fluorination approaches, DMPU-HF has shown both highe

4,5-DIHYDRO-OXAZOL-2YL DERIVATIVES

The invention relates to compounds of formula I wherein R1, R2, X, Y, and n are defined in the specification and to pharmaceutically acceptable acid addition salts thereof. The invention also provides pharmaceutical compositions and methods of manufacture

Preparation of chiral building blocks for a highly convergent vitamin E synthesis. Systematic investigations on the enantioselectivity of the sharpless bishydroxylation

The enantioselective bishydroxylation of protected 2-methylprop-2-enol 15 and 3-methylbut-3-en-1-ol 16 to give the corresponding diols 18 and 19, respectively, which can be transformed into building blocks for the synthesis of natural vitamin E, is described. It is shown that the enantioselectivity of the bishydroxylation reaction clearly depends on the type of protecting group and its distance from the alkene moiety, with 96% ee for 16a and 16f as the best and 8% ee for 15d as the lowest result.

Method for inhibiting the degradation of cartilage

Certain carboxylic acids of the formula STR1 and the pharmaceutically-acceptable salts thereof, and certain esters and amides thereof, are useful for inhibiting the degradation of articular cartilage when administered to a mammalian subject afflicted with

Prenylation of isopentenyl derivatives with 2-methyl-3-buten-2-ol

The synthesis of the regular terpene skeleton from the title compounds has been investigated, a variety of isopentenylethers proved very reactive.Similar prenylation of 3,3-dimethylallyl derivatives led to the irregular terpene skeleton.

BASIC ELIMINATION OF SULFONIUM SALTS. NEIGHBOURING GROUP INFLUENCE ON REGIOSELECTIVITY.

A simple preparation of sulfonium salts functionalized by oxygenated groups is reported.The nature and the position of the latter control the regiochemistry of elimination of the sulfonium moiety leading to selective formation of Saytsev or Hofmann olefins.