5859-84-7

Usage

Molecular Weight

202.63 g/mol

Physical State

White solid

Class

Phenol ethers

Synthesis Uses

Used in the synthesis of various pharmaceuticals and organic chemicals

Psychoactive Effects

Known to have psychoactive effects

Designer Drug Production

Used in the production of designer drugs
Benzene ring
Methanol group
Chlorine atom
Two methoxy groups

Caution Required

Handle with caution due to potential health hazards and toxicity

Upstream product

• 7311-34-4 3,5-dimethoxybenzaldehdye 
• 51903-93-6 methyl 2-chloro-3,5-dimethoxybenzoate 
• 2150-37-0 methyl 3,5-dimethoxybenzoate 
• 705-76-0 3,5-dimethoxybenzyl alcohol 
• 17275-82-0 ethyl 3,5-dimethoxybenzoate 
• 112641-63-1 2-chloro-3,5-dimethoxy-benzaldehyde 
• 1132-21-4 3,5-dimethoxybenzoic acid 

Downstream Products

• 75177-61-6 2-chloro-3,5-dimethoxybenzyl chloride 
• 1430737-52-2 tert-butyl(((1R,3aS,4S,7aR)-4-(2-chloro-3,5-dimethoxybenzyl)-4,7a-dimethyl-5-methyleneoctahydro-1H-inden-1-yl)oxy)-dimethylsilane 
• 5859-85-8 1-(bromomethyl)-2-chloro-3,5-dimethoxybenzene 
• 1430737-39-5 2-chloro-1-(iodomethyl)-3,5-dimethoxybenzene 
• 1430737-41-9 (1R,3aR,4S,7aR)-4-(2-chloro-3,5-dimethoxybenzyl)-1-hydroxy-4,7a-dimethylhexahydro-1H-inden-5(6H)-one 

Relevant academic research and scientific papers

FGFR INHIBITOR AND APPLICATION THEREOF

An azatricyclic compound (as represented by formula I) which acts as an inhibitor of fibroblast growth factor receptors (FGFR), as well as a pharmaceutical composition thereof, a preparation method, and a use therefor in the treatment of FGFR-mediated diseases. The azatricyclic compound exerts an effect by means of participating in the regulation of a plurality of processes such as cell proliferation, apoptosis, migration, neovascularization, and the like. AA%%%Formula (I).

Diastereoselective synthesis of complex cis-hexahydroindanes by reductive alkylation

An efficient and operationally simple approach to complex cis-hexahydroindanes is reported. Upon Birch reduction of unprotected, C4-alkylated tetrahydroindanols and electrophilic trapping of the tetrasubstituted enolate, cis-fused products are formed with a new stereogenic quaternary carbon. The reaction is convergent, completely diastereoselective, and shows a broad scope with regard to the electrophile.