58658-02-9

Basic information

• Product Name: 10-methyl-2-nitroacridin-9(10H)-one
• Synonyms: 10-Methyl-2-nitro-9(10H)-acridinone; 9(10H)-Acridinone, 10-methyl-2-nitro-
• CAS NO: 58658-02-9
• Molecular Formula: C₁₄H₁₀N₂O₃
• Molecular Weight: 254.2408
• Mol File: 58658-02-9.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 464°C at 760 mmHg
• Flash Point: 234.4°C
• Density: 1.37g/cm³
• Vapor Pressure: 8.64E-09mmHg at 25°C
• Refractive Index: 1.663
• CAS DataBase Reference: 10-methyl-2-nitroacridin-9(10H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 10-methyl-2-nitroacridin-9(10H)-one(58658-02-9)
• EPA Substance Registry System: 10-methyl-2-nitroacridin-9(10H)-one(58658-02-9)

Safety Data

• Hazardous Substances Data: 58658-02-9(Hazardous Substances Data)

Usage

Derivative of

Acridine

Contains

Nitro group

Potential applications

a. Fluorescent probe
b. Antitumor agent
c. DNA-binding agent

Fields of interest

Pharmaceutical and industrial

Unique structure

Promising candidate for further research and development

Synthesis and derivatization

Subjects of interest in organic chemistry

Potential biological activities

Diverse potential uses in various fields

Upstream product

• 719-54-0 10-methyl-9, 10-dihydro-9-acridinone 
• 79110-26-2 2-(N-methylanilino)-5-nitrobenzaldehyde 
• 7251-00-5 2-nitroacridone 
• 74-88-4 methyl iodide 
• 2516-96-3 2-chloro-5-nitrobenzoic acid 
• 62-53-3 aniline 
• 16927-50-7 NPB 
• 578-95-0 10H-acridin-9-one 
• 6361-21-3 2-chloro-5-nitrobenzaldehyde 
• 59670-72-3 2-chloro-5-nitrobenzaldehyde dimethylhydrazone 
• 100-61-8 N-methylaniline 
• 27996-87-8 2-fluoro-5-nitrobenzaldehye 
• 124-41-4 sodium methylate 

Downstream Products

• 58658-03-0 2-amino-10-methyl-9-acridanone 

Relevant articles and documents

A new visible light triggered Arrhenius photobase and its photo-induced reactions

Arrhenius photobases are of potential use for excited state hydroxide ion dissociation (ESHID), photo-induced pOH jump experiments, and base-catalyzed reactions. However, previously studied Arrhenius photobases have to be excited by UV light and undergo ESHID reactions only in protic solvents. These characteristics have become a disadvantage to their application in many fields of research. In this work, we have designed and synthesized a new Arrhenius photobase (NO2-Acr-OH), the ESHID reaction of which is readily triggered by visible light excitation. In contrast to previously studied Arrhenius photobases, NO2-Acr-OH undergoes ESHID reactions in protic solvents as well as in polar aprotic solvents. Solvent-dependent photo-induced reactions of NO2-Acr-OH are comprehensively studied by time-resolved fluorescence spectroscopy. Molecular designs for visible light triggered acridinol-based Arrhenius photobases with a large ΔpKb value are proposed.

SULFONATED 2(7)-AMINOACRIDONE AND 1-AMINOPYRENE DYES AND THEIR USE AS FLUORESCENT TAGS, IN PARTICULAR FOR CARBOHYDRATE ANALYSIS

Sulfonated 2(7)-aminoacridone and 1-aminopyrene dyes and their use as fluorescent tags, in particular for carbohydrate analysis The invention relates to fluorescent dyes with multiple negatively charged groups in their ionized form which are aminoacridone

Two-photon fluorescent probe 10-methyl-2-amino-acridone as well as preparation method and application thereof

The invention discloses two-photon fluorescent probe 10-methyl-2-amino-acridone as well as a preparation method and application thereof. The 10-methyl-2-amino-acridone is used as a fluorescent probe and is used for living imaging of cells and zebra fishes. The structural formula of the 10-methyl-2-amino-acridone is shown in the description. The compound has good water solubility; emission wavelength of the compound is a green light wave band; with good two-photon activity, bioautofluorescence and self-absorption can be well reduced, and the compound is successfully applied to imaging of the cells and the zebra fishes; meanwhile, the compound has good electrochemical activity, and is expected to be applied to the field of electrochemical sensing as a novel electro-active indicator.