58688-30-5Relevant academic research and scientific papers
A palladium-catalyzed asymmetric allylic alkylation approach to α-quaternary γ-butyrolactones
De Oliveira, Marllon Nascimento,Fournier, Jeremy,Arseniyadis, Stellios,Cossy, Janine
supporting information, p. 14 - 17 (2017/11/27)
The Pd-catalyzed asymmetric allylic alkylation (Pd-AAA) of enol carbonates derived from γ-butyrolactones is reported, affording the corresponding enantioenriched α,α′-disubstituted γ-butyrolactones in both high yields and high enantioselectivities (up to 94% ee). This method was eventually applied to the synthesis of chiral spirocyclic compounds.
Enantioselective ketone hydroacylation using noyori's transfer hydrogenation catalyst
Murphy, Stephen K.,Dong, Vy M.
supporting information, p. 5553 - 5556 (2013/05/22)
An enantioselective ketone hydroacylation enables the direct preparation of lactones from keto alcohols. The alcohol is oxidized in situ to an aldehyde, obviating the need to prepare sensitive keto aldehyde substrates. Noyori's asymmetric transfer hydroge
Unexpected reaction of a dimethylzinc-generated THF radical with aldehydes
Yamamoto, Yasutomo,Yamada, Ken-Ichi,Tomioka, Kiyoshi
, p. 795 - 797 (2007/10/03)
A dimethylzinc-air-generated THF radical reacted with aldehydes at the β-position of an α-oxygenated THF.
