58711-31-2

Upstream product

• 105-36-2 ethyl bromoacetate 
• 583-60-8 2-Methylcyclohexanone 
• 16178-87-3 2-methyl-2-allylcyclohexanone 
• 854448-63-8 (3-ethoxycarbonyl-1-methyl-2-oxo-cyclohexyl)-acetic acid ethyl ester 

Downstream Products

• 810681-62-0 1-but-3-ynyl-3a-methyl-1,3,3a,4,5,6-hexahydro-2H-indol-2-one 
• 1057255-76-1 1-(3-fluoro-benzyl)-3a-methyl-1,3,3a,4,5,6-hexahydro-indol-2-one 
• 1057255-92-1 1-(2,3-dichloro-benzyl)-3a-methyl-1,3,3a,4,5,6-hexahydro-indol-2-one 
• 1057255-79-4 1-(4-fluoro-benzyl)-3a-methyl-1,3,3a,4,5,6-hexahydro-indol-2-one 
• 1057255-82-9 1-(3,4-difluoro-benzyl)-3a-methyl-1,3,3a,4,5,6-hexahydro-indol-2-one 
• 1057255-89-6 1-(3-chloro-benzyl)-3a-methyl-1,3,3a,4,5,6-hexahydro-indol-2-one 
• 1057255-84-1 1-(2,4-dichloro-benzyl)-3a-methyl-1,3,3a,4,5,6-hexahydro-indol-2-one 
• 1057255-96-5 1-(3-methoxy-benzyl)-3a-methyl-1,3,3a,4,5,6-hexahydro-indol-2-one 
• 203244-99-9 1-benzyl-3a-methyl-1,3,3a,4,5,6-hexahydroindol-2-one 
• 844473-97-8 3a-methyl-1,3,3a,4,5,6-hexahydroindol-2-one 
• 678183-45-4 1-benzyl-7-bromo-3a-methyl-1,3,3a,4,5,6-hexahydroindol-2-one 
• 810681-59-5 2,7a-dimethyl-3,4,7,7a,8,9,10,11-octahydropyrido[2,1-i]indol-6-one 
• 810681-60-8 2,7a-dimethyl-1,4,7,7a,8,9,10,11-octahydropyrido[2,1-i]indol-6-one 
• 810681-58-4 3a-methyl-1-(3-methylbut-3-enyl)-1,3,3a,4,5,6-hexahydro-2H-indol-2-one 

Relevant academic research and scientific papers

Sulfonamide peri-substituted bicyclics for occlusive artery disease

Acyl sulfonamide, peri-substituted, fused bicyclic ring compounds useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed. The compounds are of the general formula A representative example is:

ARYL SULFONAMIDE PERI-SUBSTITUTED BICYCLICS FOR OCCLUSIVE ARTERY DISEASE

Aryl sulfonamide, peri-substituted, fused bicyclic ring compounds useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed. The compounds are of the general formula (I). A representative example is formula (II

CARBOXYLIC ACID PERI - SUBSTITUTED BICYCLICS FOR OCCLUSIVE ARTERY DISEASE

Peri-substituted, fused bicyclic ring carboxylic acids useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed.

Ring-Chain Tautomerism Provides a Route to 7a-Hydroxy-3a-methyl-2,7-dioxoperhydrobenzofuran. Synthesis of the Hydroxy γ-Lactone Substructure of Myrocin and Other Bioactive Natural Products

(2-Oxocyclohexyl)acetic acid 10 was converted into bicyclic alkoxy γ-lactones 12a-d via intermediate chloro lactone 11 and alkanolysis.Similarly, lactones 15a,b and 18 were prepared.In contrast, simple ring-chain tautomerism directly afforded the title heterocycle 28, a crystalline, stable and welldefined compound.The angular methyl group seems essential for the spontaneous lactonization. 5,5-Dialkoxy-4-oxocarboxylic acids 26a, b without an angular methyl group did not cyclize to bicyclic hydroxy γ-lactones. - Key Words: Hydroxy lactone, 5-membered, (lactol) tautomer / 4-Oxocarboxylic acids / Keto-cyclol tautomerism.

Carbazole acetic acid derivatives

Tetrahydrocyclopent[b]indole-3-acetic acid, tetrahydrocarbazole-1-acetic acid and hexahydrocyclohept[b]-indole-6-acetic acid derivatives in which the carbon bearing alkyl, lower alkenyl or lower cycloalkyl are disclosed. The compounds are useful antiinflammatory agents and methods for their preparation and use are described.

Cycloalkanoindoles. I. Synthesis and antiinflammatory actions of some acidic tetrahydrocarbazoles, cyclopentindoles, and cycloheptindoles

A novel series of acidic cycloalkanoindoles comprising tetrahydrocarbazole, cyclopentindole, and cycloheptindole 1 acetic acids has been synthesized via the Fischer indolization between a phenylhydrazine and a 1 alkyl 2 oxocycloalkaneacetic acid ester. Th