58714-95-7Relevant academic research and scientific papers
Stereochemistry and Mechanism of the Nickel-catalysed Hydrocyanation of Conjugated Dienes
Baeckvall, Jan-E.,Andell, Ove S.
, p. 260 - 261 (1984)
Nickel-catalysed addition of deuterium cyanide to cyclohexa-1,3-diene was shown to occur with cis stereochemistry, indicating that a cis-migration of co-ordinated cyanide takes place in an intermediate ?-allylnickel complex.
(2-hydroxy)ethyl-thioureas useful as modulators of alpha2B adrenergic receptors
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, (2008/06/13)
Compounds of formula (i) and of formula (ii) wherein the symbols have the meaning disclosed in the specification, specifically or selectively modulate α2B and/or α2C adrenergic receptors in preference over α2A adrenergic receptors, and as such are useful for alleviating chronic pain and allodynia and have no or only minimal cardivascular and/or sedatory activity.
Diastereoselectivity in the epoxidation of substituted cyclohexenes by dimethyldioxirane
Murray, Robert W.,Singh, Megh,Williams, Brian L.,Moncrieff, Hazel M.
, p. 1830 - 1841 (2007/10/03)
Three series of compounds based on the cyclohexene framework have been epoxidized by dimetbyldioxirane. A pronounced dependence of epoxide diastereoselectivity on substituent has been observed. In addition there is a solvent influence on this stereoselectivity. The results have been explained by invoking steric, H-bonding, and dipole - dipole influences on the epoxide stereochemistry.
