58751-63-6

Upstream product

• 1083-30-3 dihydrochalcone 
• 71-43-2 benzene 
• 4393-06-0 1-Phenyl-2-propen-1-ol 
• 577-19-5 2-nitrophenyl bromide 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 3958-60-9 2-nitrophenylmethyl bromide 
• 53744-31-3 2-nitrochalcone 
• 1466-88-2 2-nitrocinnamic aldehyde 
• 98-80-6 phenylboronic acid 
• 98-86-2 acetophenone 
• 552-89-6 2-nitro-benzaldehyde 

Downstream Products

• 24005-23-0 2-phenyl-1,2,3,4-tetrahydroquinoline 
• 108716-29-6 3-(2-nitro-phenyl)-1-phenyl-propan-1-ol 
• 612-96-4 2-Phenylquinoline 
• 3377-72-8 2-benzylindole 

Relevant academic research and scientific papers

The Heck reaction of allylic alcohols catalysed by an N-heterocyclic carbene-Pd(ii) complex and toxicity of the ligand precursor for the marine benthic copepod: Amphiascoides atopus

The palladium-catalysed reaction of aryl halides and allylic alcohols is an attractive method for obtaining α,β-unsaturated aldehydes and ketones, which represent key intermediates in organic synthesis. In this context, a 1,2,3-triazol-5-ylidene (aNHC)-based palladium(ii) complex formed in situ has been found to be a selective catalyst for the syntheses of building blocks from the corresponding aryl halides and allylic alcohols, with yields ranging from 50% to 90%. The lack of toxic effects of the ligand precursor (1,2,3-triazolium salt) of the palladium(ii) complex for the harpacticoid copepod Amphiascoides atopus allowed us to contrast the efficiency of the catalytic system with the potential impact of the principal waste chemical in global aquatic ecosystems, which has not been previously addressed.

Applications of N1-long-chain alkyl-N3-piperidine ethylimidazole salt

The invention provides applications of an N1-long-chain alkyl-N3-piperidine ethylimidazole salt, wherein the ionic liquid has surface activity and double alkalinity, and can catalyze the synthesis ofchalcone compounds. The method for synthesizing a chalcone compound under the catalysis of the ionic liquid comprises: mixing substituted benzaldehyde, substituted acetophenone and water, adding an ionic liquid, and carrying out a reaction; and after the reaction is finished, carrying out separation purification to obtain a product chalcone compound, wherein the separated catalyst-containing solution can be applied. According to the invention, the problems of strong corrosivity of composite catalyst systems such as ionic liquids/alkalis, ionic liquids/acid and the like, and high ionic liquid consumption, low yield and the like in the chalcone preparation process only using alkaline ionic liquid catalysts are overcome, and the reaction yield in the catalytic synthesis of chalcone compoundsreaches more than 85%; and the method for preparing the chalcone compound through catalysis has characteristics of easy and convenient operation, easy product separation, environmentally friendly solvent and repeated use of the catalyst.

Dirhodium(ii)/P(t-Bu)3 catalyzed tandem reaction of α,β-unsaturated aldehydes with arylboronic acids

Phosphine ligated dirhodium(ii) acetate is advocated as a catalyst for the synthesis of aryl alkyl ketones by the tandem reaction of α,β-unsaturated aromatic or aliphatic aldehydes with arylboronic acids. This tandem procedure included arylation followed by the isomerization reaction. This method exhibits good functional group tolerance and has a broad substrate scope. With the conjugated aldehydes, the one-step synthesis of γ,δ-unsaturated ketones was realized through this reaction. It is noteworthy that the length of the Rh-P bond is an important factor affecting catalytic reactions. The comparative analysis of the crystal structures of axially alkylphosphane and arylphosphane ligated dirhodium(ii) acetate revealed that the shorter Rh-P bond length favors the isomerization process as compared to the longer one. In addition, the dirhodium(ii) compound can be recovered after the completion of the reaction.

Organocatalyzed biomimetic selective reduction of c=c double bonds of chalcones

In this article, we reported a biomimetic approach for chemoselective reduction of C=C double bonds in chalcones under metal and acid free conditions, that relies on olefin activation by hydrogen bond formation. The process requires only catalytic amount of ephedrine as hydrogen bond donor and utilizes Hantzsch esters for transfer hydrogenation.

Visible-light-induced intermolecular atom-transfer radical addition of benzyl halides to olefins: Facile synthesis of tetrahydroquinolines

Cu(dap)2Cl has been utilized as a visible-light photoredox catalyst for the atom-transfer radical addition (ATRA) of benzyl halides to styrenes and silyl enol ethers. The resulting ATRA products can be readily converted into tetrahydroquinoline

The Heck reaction of allylic alcohols catalysed by an air-stable phosphinito complex of palladium(II)

The Heck coupling of aryl bromides with primary and secondary allylic alcohols, performed in the presence of an air-stable- phosphinito complex of palladium(II), produced the corresponding carbonyl compounds. Reactions with tertiary allylic alcohols under the same conditions generated the aromatic conjugated alcohols. Georg Thieme Verlag Stuttgart · New York.