58794-05-1 Usage
Uses
Used in Nicotine Addiction Treatment:
α-Methyl-3-isoquinolinemethanol is used as a therapeutic agent for nicotine addiction, aiming to reduce the reinforcing effects of nicotine. By blocking nicotinic acetylcholine receptors, it diminishes the pleasurable and addictive properties of nicotine, thus aiding in smoking cessation and reducing the risk of relapse.
Used in Psychiatric Disorders Management:
In the field of psychiatry, α-Methyl-3-isoquinolinemethanol is utilized as a potential treatment for certain psychiatric disorders, such as depression and anxiety. Its mechanism of action involves the modulation of neurotransmitter activity at nicotinic acetylcholine receptors, which may contribute to the alleviation of symptoms associated with these conditions.
However, the clinical use of α-Methyl-3-isoquinolinemethanol is tempered by its adverse effects, including dizziness, sedation, and dry mouth. Additionally, there is a potential for abuse and dependence, which necessitates careful consideration and monitoring in its therapeutic applications across different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 58794-05-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,7,9 and 4 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 58794-05:
(7*5)+(6*8)+(5*7)+(4*9)+(3*4)+(2*0)+(1*5)=171
171 % 10 = 1
So 58794-05-1 is a valid CAS Registry Number.
58794-05-1Relevant academic research and scientific papers
Homochiral isoquinolines by lipase-catalysed resolution and their diastereoselective functionalisation
Guanti, Giuseppe,Riva, Renata
, p. 1185 - 1200 (2007/10/03)
Kinetic resolution of racemic isoquinoline alcohols and acetates has been successfully accomplished using lipases as chiral catalysts. The diastereoselective functionalisation of the isoquinoline moiety through the addition of C-nucleophiles to O-protected alcohol 9a in the presence of phenyl chloroformate has been carried out and dihydroquinolyl alcohol derivatives with high diastereomeric excess have been prepared.
Alpha-substituted pyrimidine-thioalkyl and alkylether compounds as inhibitors of viral reverse transcriptase
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, (2008/06/13)
The subject invention relates to pyrimidine-thioalkyl and alkylether compounds of Formula (I) and pyrimidine-thioalkyl and alkylethers of Formula (IA), namely the compounds of Formula (I) where R 4 is selected from the group consisitng of --H or --NR 15 R 16 where R 15 is --H and R 16 is --H, C 1 -C 6 alkyl, NH 2 or R 15 and R 16 taken together with the --N form 1-pyrrolidino, 1-morpholino or 1-piperidino; and R 6 is selected from the group consisting of --H, or halo (preferably --Cl); with the overall proviso that R 4 and R 6 are not both --H. The compounds of Formula (IA) are useful in the treatment of individuals who are HIV positive being inhibitors of viral reverse transcriptase. STR1
