588-43-2

Usage

Uses

Used in Organic Synthesis:
Tributyl orthoformate is used as a reagent in organic synthesis for the formation of acetals and orthoesters, which are important in the synthesis of various organic compounds.
Used in Chemical Processes as a Solvent:
In various chemical processes, tributyl orthoformate is utilized as a solvent, facilitating reactions and improving the efficiency of the process.
Used in the Production of Formic Acid and Butanol:
Tributyl orthoformate is an important intermediate in the production of formic acid and butanol. Upon hydrolysis in the presence of air, it breaks down to form these compounds, which have various applications in the chemical industry.
Used in the Pharmaceutical Industry:
Tributyl orthoformate may be used in the pharmaceutical industry as a reagent for the synthesis of pharmaceutical compounds, given its role in the formation of acetals and orthoesters.
Used in the Agrochemical Industry:
In the agrochemical industry, tributyl orthoformate could be employed as a reagent in the synthesis of agrochemicals, such as pesticides and herbicides, due to its ability to form acetals and orthoesters.
Used in the Flavor and Fragrance Industry:
Tributyl orthoformate may also find use in the flavor and fragrance industry, where it can be employed in the synthesis of complex organic compounds that contribute to the scents and tastes of various products.

InChI:InChI=1/C13H28O3/c1-4-7-10-14-13(15-11-8-5-2)16-12-9-6-3/h13H,4-12H2,1-3H3

Upstream product

• 122-51-0 orthoformic acid triethyl ester 
• 71-36-3 butan-1-ol 
• 75-47-8 iodoform 
• 67-66-3 chloroform 
• 74-90-8 hydrogen cyanide 
• 6267-24-9 tris(ethylsulfanyl)methane 
• 544-16-1 n-Butyl nitrite 
• 701-56-4 4-methoxy-N,N-dimethylanilne 
• 586-77-6 4-bromo-N,N-dimethylaniline 
• 111-34-2 -butyl vinyl ether 
• 380883-31-8 1-phenylcyclohexa-2,5-diene-1-carboxylic acid 

Downstream Products

• 109-69-3 n-Butyl chloride 
• 592-84-7 n-butyl formate 
• 136-60-7 benzoic acid, butyl ester 
• 871-22-7 dibutyl acetal 
• 13112-65-7 Pentanal-(1)-dibutylacetal 
• 2204-81-1 N-Tosyl-N-butyl-carbamidsaeurebutylester 
• 68057-50-1 1-chloro-4-dibutoxymethoxy-benzene 
• 85733-11-5 2-phenyl-3-butyl-2-heptenal 
• 542-52-9 Dibutyl carbonate 
• 123-72-8 butyraldehyde 
• 106-97-8 n-butane 
• 82343-41-7 4-methoxybenzaldehyde di-n-butyl acetal 
• 49758-73-8 Dibutoxymethoxy-benzene 
• 2892-62-8 3,4-dibutoxy-3-cyclobutene-1,2-dione 

Relevant academic research and scientific papers

Green preparing orthoformate cleaning process

The invention provides a green process for preparing orthoformate. A hydrogen chloride alcohol solution is prepared from a byproduct hydrogen chloride tail gas of the chlorine-related synthesis industry and then is slowly added into a reaction system, so that loss caused by escape of hydrocyanic acid is reduced, the yield is increased, great equipment corrosion caused by the byproduct hydrochloric acid prepared by the companies is avoided, the economic additional value of the byproduct hydrogen chloride is greatly increased, three wastes are avoided, the byproduct only comprises ammonium chloride, resources are reasonably utilized, and the green process for preparing the orthoformate is an environment-friendly production process and has a good social benefit.

Preparation of 1-phenylcyclohexa-2,5-diene-1-carboxylates and their use in free-radical mediated syntheses

Synthetic routes to pure 1-phenylcyclohexa-2,5-diene-1-carboxylic acid and derived esters were developed. Esters containing appropriately unsaturated side chains generated the corresponding alkenyl radicals and hence gave good yields of 5-exo ring closure products in organotin-free reactions. Extrusion of phenyl radicals from the intermediate cyclohexadienyl type radicals was not observed, and this alternative β-scission did not compete under any conditions. Yields from alkylations of olefins in analogous intermolecular processes were, however, poor. As a spin-off from the research, it was found that 1-phenylcyclohexa-2,5-diene-1-carboxylic acid (6) was a useful source of hydroxyformyl (formate) radicals in organic solvents.

AROMATIC TERTIARY AMINES AND n-BUTYL NITRITE

The reaction between alkyl nitrites, particularly n-butyl nitrite, and tertiary aromatic amines under a variety of experimental conditions promptly yielded products of N-dealkylation-N-nitrosation, ring nitration, ipso-substitution and, occasionally, combinations of these processes.Aminoethers were detected as final products and intermediates on the way to N-nitrosations.Reaction pathways are suggested for some of the observed behaviours on the basis of experimental evidences whereas other alternatives are discarded.

Action d'organometalliques sur les dialkylphenylorthoformiates. Preparation facile d'acetals

The reaction of dialkylphenylorthoformiates with organometallic compounds proceeds with a good yield, at room temperature, giving the corresponding dialkylacetals ; it allows an easy preparation of acetals which are otherwise difficult to prepare.