58805-10-0Relevant articles and documents
A Kulinkovich entry into tertiary N-acyliminium ion chemistry
Ollero, Lourdes,Mentink, Gertjan,Rutjes, Floris P. J. T.,Speckamp, W. Nico,Hiemstra, Henk
, p. 1331 - 1334 (1999)
(formula presented) Subjection of N-alkenylimides to Kulinkovich cyclopropanation conditions led to different types of N,O-acetals, which were used as precursors for tertiary N-acyliminium ion chemistry. In this way, a variety of bi- and tricyclic lactams were efficiently synthesized.
TRICYCLIC COMPOUND SERVING AS IMMUNOMODULATOR
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Paragraph 0339-0340, (2019/01/04)
Provided are compounds of formula I and formula II or pharmaceutically acceptable salts of the compounds and pharmaceutical compositions thereof. The compounds of formula I and formula II or the pharmaceutically acceptable salts of the compounds provide indole 2,3-dioxygenase (IDO) inhibitory activity and are capable of treating IDO-mediated immunosuppressive diseases, such as infectious diseases or cancer.
Stereoselective synthesis of amido and phenyl azabicyclic derivatives via a tandem aza prins-ritter/friedel-crafts type reaction of endocyclic N-acyliminium ions
Indukuri, Kiran,Unnava,Deka, Manash J.,Saikia, Anil K.
, p. 10629 - 10641 (2013/11/19)
A simple protocol is described for the synthesis of amido and phenyl hexahydroindolizin-3(2H)-one, hexahydro-1H-quinolizin-4(6H)-one, and 1,3,4,10b-tetrahydropyrido[2,1-a]isoindol-6(2H)-one derivatives via endo-trig (aza-Prins type) cyclization followed b
β-, γ- and δ-Lactams as conformational constraints in ring-closing metathesis
Tarling, Chris A.,Holmes, Andrew B.,Markwell, Roger E.,Pearson, Neil D.
, p. 1695 - 1701 (2007/10/03)
The azabicycloalkenones 5, 6 and 7 were formed in excellent yields via ring-closing metathesis of the bis-alkenyl precursors 1, 2 and 3.
