58821-35-5

Upstream product

• 13866-14-3 cis-1-benzoyl-2,3-diphenylaziridine 
• 100-52-7 benzaldehyde 
• 3723-23-7 2-amino-1,2-diphenylethanone 
• 530-36-9 2-amino-1,2-diphenylethanol 
• 55-21-0 benzamide 
• 1605-06-7 cis-2,3-diphenylaziridine 
• 98-88-4 benzoyl chloride 
• 79102-23-1 trans-1-benzoyl-2,3-diphenylaziridine 
• 530-36-9 erythro-2-amino-1,2-diphenylethanol 
• 825-60-5 benzimidic acid ethyl ester 

Downstream Products

• 71027-98-0 trans-2,4,5-triphenyl-Δ²-oxazoline 

Relevant academic research and scientific papers

Synthesis of some derivatives of 4,5-dihydrooxazoles

Benzaldehyds with sodium amide in the presence of thiourea in tetrahydro furan at room temperature gave various 2,4,5-triphenyl-4,5-dihydrooxazoles. The thiourea-catalyzed condensation of the benzaldehyde yielded 2-amino-1,2- diphenylethanone. Reduction of 2-amino-1,2-diphenylethanone was performed with hydride from Cannizzaro reaction to give 2-amino-1,2-diphenylethanols. The 4,5-dihydrooxazole ring formation of the 2-amino-1,2-diphenylethanol and benzamide gave the desired 4,5-dihydrooxazole.

Copper-catalyzed oxidative desulfurization-promoted intramolecular cyclization of thioamides using molecular oxygen as an oxidant: An efficient route to five- To seven-membered nitrogen-containing heterocycles

Copper-catalyzed oxidative desulfurization-promoted intramolecular cyclization reactions of thioamides take place under neutral and mild conditions by using molecular oxygen as an oxidant. The process yields a wide variety of nitrogen-containing heterocyc

Acid catalysed rearrangement of some N-acylaziridines

The reaction of N-acylaziridines 1 with concentrated sulfuric acid leads to the oxazolines 3 and/or amidoalcohols 4. The geometry of the aziridines 1 is discussed and an ionic mechanism is proposed.

Friedel-Crafts reactions of some N-acylaziridines: Oxazolines as intermediates

Without heat supply, AlCl3 and 3-substituted 1-acyl-2-phenylaziridines 1a,b, and 2b in benzene provided the respective Friedel-Crafts products 3a,b, and 4b (acylated 1-substituted 2,2-diphenylethylamines) which in part were further converted to 1,1,2,2-teraphenylethane (5). Oxazolines 6a,b, and 7b were also found. It is shown by means of 2,4,5-triphenyloxazoline 6b that oxazolines are intermediates for 3, 4, and 5. The uncommon heterolysis of these particular oxazolines is discussed.

Evolutions differentes de radicaux anions formes par voie chimique ou electrochimique

Chemical and electrochemical reductions of N-aroylaziridines 1 are described and compared.The first step is a single electron transfer (1 +e -> 1-. -> 1'-.).But compounds obtained from 1'-. are depending on the method used way followed: chemical reduction of N-cinnamoylaziridine 1e provides pyrrolidone 10e; but oxazoline 11e is available by electrochemical reduction of the same starting material 1e.Counter ion seems responsible of these different results.In agreement with this hypothesis, it is shown that pyrrolidone 10e is obtained from 1j only in presence of a counter ion.

Ring Opening of Aziridines by Different Fluorinating Reagents: Three Synthetic Routes to α,β-Fluoro Amines with Different Stereochemical Pathways

The syntheses of α,β-fluoro amines from the reaction of secondary aziridines with either Olah's reagent (HF, pyridine) or anhydrous hydrogen fluoride and of N-activated aziridines with partially neutralized Olah's reagent (NR3-nHF) are reported.The stereo