588718-08-5Relevant articles and documents
A new class of high affinity thyromimetics containing a phenyl-naphthylene core
Hangeland, Jon J.,Friends, Todd J.,Doweyko, Arthur M.,Mellstr?m, Karin,Sandberg, Johnny,Grynfarb, Marlena,Ryono, Denis E.
, p. 4579 - 4584 (2007/10/03)
High affinity thyromimetics containing a novel phenyl-naphthylene core are reported. The functionalized core is readily accessible via a Suzuki coupling protocol. Examples of this new class of TR ligands have sub-nanomolar binding affinities for the TRβ r