59050-41-8 Usage
Derivative of indole
The compound is derived from the indole structure, which is a bicyclic aromatic organic compound that is a building block for many natural and synthetic compounds.
Carboxylic acid functional group
The presence of a carboxylic acid group (-COOH) in the compound contributes to its chemical reactivity and potential applications in the synthesis of other organic compounds.
Potential building block for pharmaceuticals
1-METHYL-2-PHENYL-1H-INDOLE-3-CARBOXYLIC ACID can be used as a starting material for the synthesis of various pharmaceuticals due to its unique chemical structure.
Medicinal properties
The compound has been studied for its potential as an anti-inflammatory and anti-cancer agent, indicating its possible use in the development of new drugs for the treatment of inflammation and cancer.
Applications in material development
The compound may have potential applications in the development of new materials, possibly due to its unique chemical structure and reactivity.
Precursor for synthesis of other organic compounds
1-METHYL-2-PHENYL-1H-INDOLE-3-CARBOXYLIC ACID can serve as a precursor for the synthesis of other organic compounds, further expanding its potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 59050-41-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,0,5 and 0 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 59050-41:
(7*5)+(6*9)+(5*0)+(4*5)+(3*0)+(2*4)+(1*1)=118
118 % 10 = 8
So 59050-41-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H13NO2/c1-17-13-10-6-5-9-12(13)14(16(18)19)15(17)11-7-3-2-4-8-11/h2-10H,1H3,(H,18,19)
59050-41-8Relevant articles and documents
Me2AlCl-mediated carboxylation, ethoxycarbonylation, and carbamoylation of indoles
Nemoto, Koji,Tanaka, Shinya,Konno, Megumi,Onozawa, Satoru,Chiba, Masafumi,Tanaka, Yuuki,Sasaki, Yosuke,Okubo, Ryo,Hattori, Tetsutaro
, p. 734 - 745 (2016/01/15)
Various 1-methyl-, 1-triisopropylsilyl-, and 1-benzylindoles are carboxylated under CO2 pressure (3.0 MPa) with the aid of 1.0 molar equiv of Me2AlCl to give 1-substituted indole-3-carboxylic acids in good to excellent yields. Mechanistic studies suggest that the intermediate, an indol-3-ylaluminum ate complex, was reversibly formed by electrophilic addition of Me2AlCl to the substrate followed by deprotonation of the resulting adduct. This method is successfully extended to alkoxycarbonylation with ethyl chloroformate and carbamoylation with naphthalen-1-yl isocyanate, which afford ethyl indole-3-carboxylates and N-naphthalen-1-ylindole-3-carboxamides, respectively.
Fluorescent diarylindoles by palladium-catalyzed direct and decarboxylative arylations of carboxyindoles
Miyasaka, Mitsuru,Fukushima, Azusa,Satoh, Tetsuya,Hirano, Koji,Miura, Masahiro
scheme or table, p. 3674 - 3677 (2009/12/25)
A study was conducted to demonstrate the palladium-catalyzed 2,3-diarylation of carboxyindole derivatives with acryl bromides. The study also performed ester hydrolysis in the sequence to demonstrate a practical route to 2,3-diarylindoles that had differe
Photocarboxylation in the Presence of Aromatic Amines and Carbon Dioxide
Ito, Yoshikatsu,Uozu, Yoshihiro,Matsuura, Teruo
, p. 562 - 564 (2007/10/02)
Phenylethylenes (1), biphenyl, and 1-methyl-2-phenylindole underwent carboxylation upon photolysis in the presence of aromatic amines (2) and carbon dioxide.
