6462-31-3

Upstream product

• 7570-91-4 methyl mesityl sulphide 
• 59057-35-1 2,4,6-trimethylbenzenesulphinic acid 
• 124-63-0 methanesulfonyl chloride 
• 108-67-8 1,3,5-trimethyl-benzene 
• 1912-32-9 n-butyl methanesulfonate 
• 41138-92-5 methanesulfonyl bromide 
• 558-25-8 methyl fluorosulfonate 
• 1077-62-9 SnMe₃(C₆H₂Me₃-2,4,6) 
• 7143-01-3 Methanesulfonic anhydride 
• 75-75-2 methanesulfonic acid 
• 1541-10-2 mesitylthiol 
• 16182-15-3 2,4,6-trimethylbenzenesulfonohydrazide 
• 868-85-9 Dimethyl phosphite 

Downstream Products

• 21134-15-6 1-(4-(methylsulfonyl)phenoxy]benzene 
• 47189-05-9 1-phenoxy-4-(phenylsulfonyl)benzene 
• 82961-62-4 4-Ethoxyphenyl ethyl sulphone 
• 3517-90-6 p-anisyl methyl sulfone 
• 3112-84-3 4-methoxyphenyl phenyl sulfone 
• 108-67-8 1,3,5-trimethyl-benzene 
• 510730-06-0 5-methyl-1-(2,4,6-trimethylphenylsulfonyl)-5-hexen-2-one 
• 510730-14-0 6-methyl-1-(2,4,6-trimethylphenylsulfonyl)-5-hepten-2-one 
• 510730-11-7 5-bromo-1-(2,4,6-trimethylphenylsulfonyl)-5-hexen-2-one 
• 907195-87-3 5-(3,4-dimethoxyphenyl)-1-(2,4,6-trimethylphenylsulfonyl)-5-hexen-2-one 
• 907195-94-2 5-(3,4-di-tert-butyldimethylsilyloxyphenyl)-1-(2,4,6-trimethylphenylsulfonyl)-5-hexen-2-one 
• 880480-06-8 5-Methylene-1-(2,4,6-trimethyl-benzenesulfonyl)-tetradecan-2-one 
• 1015073-34-3 C₃₂H₄₀O₄SSi 

Relevant academic research and scientific papers

High Chemoselectivity in the Construction of Aryl Methyl Sulfones via an Unexpected C-S Bond Formation between Sulfonylhydrazides and Dimethyl Phosphite

A highly chemoselective route to aryl methyl sulfones via an unexpected C S bond formation between sulfonylhydrazides and dimethyl phosphite catalyzed by NaI under mild conditions has been established. This transformation provides an alternative and metal-free pathway to acquire various aryl methyl sulfones in good to excellent yields. Notably, dimethyl phosphite was employed as a stable and readily available alkyl source.

Enantioselective copper catalysed intramolecular C-H insertion reactions of α-diazo-β-keto sulfones, α-diazo-β-keto phosphine oxides and 2-diazo-1,3-diketones; the influence of the carbene substituent

Enantioselectivities in C-H insertion reactions, employing the copper-bis(oxazoline)-NaBARF catalyst system, leading to cyclopentanones are highest with sulfonyl substituents on the carbene carbon, and furthermore, the impact is enhanced by increased steric demand on the sulfonyl substituent (up to 91%ee). Enantioselective intramolecular C-H insertion reactions of α-diazo-β-keto phosphine oxides and 2-diazo-1,3-diketones are reported for the first time.

Rapid and mild sulfonylation of aromatic compounds with sulfonic acids via mixed anhydrides using Tf2O

An efficient and direct sulfonylation of aromatic compounds with sulfonic acids is described via mixed anhydrides in short reaction times using Tf2O in nitromethane at room temperature.

Direct sulfonylation of aromatic rings with aryl or alkyl sulfonic acid using supported P2O5/Al2O3

Direct sulfonylation of aromatic rings with aryl or alkyl sulfonic acid supported P2O5/Al2O3 (w/w 50%) under heterogeneous conditions in short reaction time and high yields. Copyright Taylor & Francis Inc.

Investigations on the iron-catalyzed asymmetric sulfide oxidation

The development of an enantioselective sulfide oxidation involving a chiral iron catalyst and aqueous hydrogen peroxide as oxidant is described. In the presence of a simple carboxylic acid, or a carboxylate salt, the reaction affords sulfoxides with remarkable enantioselectivities (up to 96% ee) in moderate to good yields. The influence of the structure of the additive on the reaction outcome is reported. In the sulfoxide-to-sulfone oxidation a kinetic resolution (with s = 4.8) occurs, which, however, plays only a negligible role in the overall enantioselective process. Furthermore, a positive nonlinear relationship between the ee of the product and that of the catalyst has been found. On the basis of these observations, a possible catalyst structure is proposed.

Total Synergistic effect between triflic acid and bismuth(IIIr antimony(III) chlorides in catalysis of the Methanesulfonylation of Arenes

A total synergistic effect between bismuth(III) or antimony(III) chlorides and triflic acid has been observed in the Friedel-Crafts methanesulfonylation of arenes and has resulted in the development of the first efficient catalytic systems usable for the methanesulfonylation of both activated and deactivated arenes. A proposed mechanism to explain the observed effects is also discussed. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.

Fe-pillared bentonite-an efficient catalyst for sulfonylation of arenes using aryl and alkyl sulfonyl chlorides

Fe-pillared bentonite (Fe-PILC) was shown to be an extremely efficient catalyst for the sulfonylation of activated as well as unactivated carbocyclic aromatic compounds and heterocyclic aromatic compounds. The catalyst was also found to be recyclable.

An efficient method for aromatic Friedel-Crafts alkylation, acylation, benzoylation, and sulfonylation reactions

Aromatic electrophilic substitution reactions such as alkylation, acylation, benzoylation, and sulfonylation were studied in the presence of a catalytic amount of Cu(OTf)2 and Sn(OTf)2. Cu(OTf)2 was very efficient for alkylation, acylation, and benzoylation reactions. However, in case of sulfonylation reactions, Sn(OTf)2 gave better results.

Friedel-Crafts sulfonylation of aromatics catalysed by solid acids: An eco-friendly route for sulfone synthesis

A mild and efficient catalytic method for Friedel-Crafts sulfonylation of arenes to the corresponding sulfones using a catalytic amount of reusable solid acid and arene- or alkanesulfonyl chlorides, sulfonic anhydrides and sulfonic acids as sulfonylating agents is described. Solid acids enable formation of a sulfone by the reaction of a sulfonic acid and an arene for the first time. In pursuit of the development of the best catalytic system, various metal-exchanged K10 montmorillonites and synthetic zeolites such as zeolite beta, zeolite Y and ZSM-5 have been screened for Friedel-Crafts sulfone synthesis. Fe3+-montmorillonite in the family of clays and zeolite beta in the family of zeolites exhibit higher activity. The activity is correlated to the presence of the right mix of Bronsted and Lewis acidic sites. The regioselective sulfonylation of toluene and naphthalene are studied in which para and beta selectivities are observed respectively. The Royal Society of Chemistry 2000.