591235-75-5Relevant academic research and scientific papers
A novel and simple asymmetric synthesis of CMI-977 (LDP-977): A potent anti-asthmatic drug lead
Gurjar, Mukund K.,Murugaiah,Radhakrishna,Ramana,Chorghade, Mukund S.
, p. 1363 - 1370 (2007/10/03)
A practical gram scale asymmetric synthesis of CMI-977 is described. A tandem double elimination of an α-chlorooxirane and concomitant intramolecular nucleophilic substitution was used as the key step. Jacobsen hydrolytic kinetic resolution and Sharpless
Kinetic resolution of aryl glycidyl ethers : A practical synthesis of optically pure β-blocker - S-metoprolol
Gurjar, Mukund K.,Sadalapure, Kashinath,Adhikari, Susanta,Sarma, Bugga V. N. B. S.,Talukdar, Arindam,Chorghade, Mukund S.
, p. 1471 - 1476 (2007/10/03)
Kinetic resolution of (±)-aryl glycidyl ethers using (R,R)-salen Co(III)OAc and water provided enantiomerically pure arylglycidyl ether and 1-arylglycerol derivatives with high enantiomeric excess. Application of this approach to (S)-metoprolol has been d
Intermediates for the synthesis of benzoxazol- and benzothiazolamine derivatives, useful as anti-anoxic agents
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, (2008/06/13)
Benzoxazol- and benzothiazolamine derivatives having anti-anoxic properties which compounds are useful in the treatment of anoxia. These compounds are produced from certain benzoxazol- and benzothizolamine intermediates.
Benzoxazol-and benzothiazolamine derivatives, useful as anti-anoxic agents
-
, (2008/06/13)
Benzoxazol-and benzothiazolamine derivatives having anti-anoxic properties which compounds are useful in the treatment of anoxia.
