59238-67-4

Upstream product

• 1886-57-3 1-tert-butyl-2-nitrobenzene 
• 6310-21-0 2-(1,1-dimethylethyl)-benzenamine 
• 93-97-0 benzoic acid anhydride 
• 98-88-4 benzoyl chloride 

Downstream Products

• 16078-33-4 (3,3-dimethylindolin-1-yl)(phenyl)methanone 
• 59238-74-3 2-[Benzoyl-(2-tert-butyl-phenyl)-amino]-benzoic acid methyl ester 
• 59238-56-1 2-[Benzoyl-(2-tert-butyl-phenyl)-amino]-benzoic acid 
• 59238-53-8 N-(4-tert-Butyl-phenyl)-benzimidic acid phenyl ester 
• 59238-71-0 2-[N-(2-tert-Butyl-phenyl)-benzimidoyloxy]-benzoic acid methyl ester 
• 59238-51-6 N-(2-tert-Butyl-phenyl)-benzimidic acid phenyl ester 
• 59238-50-5 5-tert-Butyl-2-[N-(2-tert-butyl-phenyl)-benzimidoyloxy]-benzoic acid methyl ester 

Relevant academic research and scientific papers

Copper-Catalyzed Amination of C(sp3)-H bonds: From Anilides to Indolines

Copper-catalyzed oxidative intramolecular cyclization of o-alkylated anilines via cleavage of C(sp3)-H and N-H bonds for the production of indolines is described. This approach provides a straightforward strategy for the synthesis of nitrogen-c

Cu-Catalyzed Intramolecular Amidation of Unactivated C(sp3)-H Bonds to Synthesize N-Substituted Indolines

A copper-catalyzed intramolecular amidation of unactivated C(sp3)-H bonds to construct indoline derivatives has been developed. Such an amidation proceeded well at primary C-H bonds preferred to secondary C-H bonds. The transformation owned a b

Activation of the aryl hydrocarbon receptor by methyl yellow and related congeners: structure-activity relationships in halogenated derivatives.

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates the biological action of many environmental compounds. Methyl yellow (4-dimethylaminoazobenzene; MY) is a principal azo-dye, and structurally related compounds were subjected to analysis of structure-activity relationships as AhR ligands by using a yeast AhR signaling assay. The effects of halogen-substitution among 23 halogenated MYs on the AhR ligand activity can be summarized as follows: enhancement by halogen-substitution at the ortho-position (2'- and 6'-position), and reduction by substitution at the para-position (4'-position). The greatest enhancement of the ligand activity was observed in 2',6'-dichlorinated MY (13.5-fold of MY), and its AhR ligand activity was very close to that of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the present assay system. In the study of compounds structurally related to MY, benzanilide (BA) showed almost the same AhR ligand activity as azobenzene and trans-stilbene. Furthermore, 4'-chlorobenzanilide, in which the length of the molecule is similar to that of MY, enhanced the AhR ligand activity by ortho(2')-chlorine-substitution, and the AhR ligand activity of 2',4'-dichlorobenzanilide was similar to that of 2'-chloro-MY. These results suggest that the amide bond is equivalent to the -N=N- or -CH=CH- double bond for recognition as the ligand by AhR in 1,2-diphenyl-1,2-ene derivatives.

3,5-Di-t-butylnitrosobenzene as a spin trap for N-arylamidyl free radicals

Acyl- and benzenesulphonyl-anilines with one or two t-butyl groups in ortho positions generate transient amidyl radicals, which were evidenced by traping with 3,5-di-t-butylnitrosobenzene.Spectral simulation showed the simultaneous presence of two paramag