5925-58-6

Upstream product

• 113325-32-9 1-(1-naphthyl)-1,2-diphenylethanol 
• 100-59-4 phenylmagnesium chloride 
• 90-14-2 1-Iodonaphthalene 
• 91574-95-7 trimethyl((Z)-1,2-diphenylvinyl)stannane 
• 536-74-3 phenylacetylene 
• 4044-57-9 1-phenylethynyl-naphthalene 
• 143-66-8 sodium tetraphenyl borate 
• 90767-34-3 α-naphthylmagnesiumchloride 
• 119379-68-9 (E)-1,1'-(1-Iodo-1,2-ethenediyl)bisbenzene 
• 779327-96-7 9-[1]naphthyl-xanthen-9-ol 
• 501-65-5 diphenyl acetylene 
• 6301-54-8 2-(naphthalen-1-yl)propan-2-ol 
• 630-95-5 1-naphthyldiphenylmethanol 
• 13922-41-3 1-Naphthylboronic acid 

Downstream Products

• 78811-59-3 1-(1,2-Diphenylethyl)naphthalin 
• 642-29-5 1-benzoylnaphthalene 

Relevant academic research and scientific papers

One-pot Sonogashira–Hydroarylation reaction catalyzed by anionic palladium complexes in an aqueous medium

It was found that anionic Pd(II) complexes of type [CA]2[PdCl4] and [CA]2[Pd2Cl6] (CA = imidazolium or pyridinium cation) are effective catalysts for copper-free Sonogashira coupling in an aqueous med

Employing Water as the Hydride Source in Synthesis: A Case Study of Diboron Mediated Alkyne Hydroarylation

We present an approach to utilize water as the hydride source via Pd(II)/Pd(0) catalysis. As a case study, we have achieved a diboron mediated Pd(II)-catalyzed hydroarylation of alkynes using arylboronic acids. This approach not only complements conventional reactivity of Pd via Pd(0)/Pd(II) cycle for the hydroarylation but also utilizes water as the hydride source. We believe this would particularly be beneficial in utilizing water as a reagent.

Zirconoarylation of alkynes through p-chloranilpromoted reductive elimination of arylzirconates

A novel method for the zirconoarylation of alkynes was developed. TCQ-promoted reductive elimination of arylzirconate [LiCp2ZrAr(RC=CR) ], which was prepared by the reaction of zirconocene-alkyne complexes with aryllithium compounds, afforded trisubstituted alkenylzirconocenes. This reaction can afford multi-substituted olefins with high stereoselectivity.

Palladium-catalyzed hydroarylation of alkynes with arylboronic acids

Reaction of symmetrical and unsymmetrical alkynes with arylboronic acids, using PdCl2 as catalyst source and i-Pr2NPPh2 as ligand, afforded trisubstituted alkenes with regioselectivity in good to excellent yields without a common additional acetic acid. Its efficiency has been demonstrated by its good functional groups, high yield and crowded substrates.

Palladium-catalyzed dehydroarylation of triarylmethanols and their coupling with unsaturated compounds accompanied by C-C bond cleavage

Triarylmethanols are effectively dehydroarylated and reacted with some unsaturated compounds by using an appropriate palladium catalyst system such as Pd(OAc)2-P(1-Nap)3 (1-Nap = 1-naphthyl) to give the corresponding arenes and hydro

Sequential reactions of trimethylstannyl anions with vinyl chlorides and dichlorides by the SRN1 mechanism followed by palladium-catalyzed cross-coupling processes

The reactions of trimethylstannyl ions (Me3Sn-) with vinyl chlorides in liquid ammonia give good yields of vinylstannanes. Some of them react in the dark, and others need light stimulation to react. The fact that these reactions are inhibited by radical and radical anion traps shows that they occur by the SRN1 mechanism. When the reaction takes place with 1,1-dichloro-1-alkenes, monosubstitution reduced products are formed in an E/Z mixture. The efficient synthesis of triarylolefins by Pd(0)-catalyzed cross-coupling reactions of vinylstannanes with several iodoarenes is reported. Similar yields were obtained in one-pot-type reactions.

Palladium-catalyzed stereoselective synthesis of E- and Z-1,1-diaryl or triarylolefins

A stereoselective and flexible synthesis of various E- and Z-1,1-diaryl and triarylolefins 3 was achieved from readily available vinylstannanes 1 via stereospecific iodo-destannylation and subsequent palladium-catalyzed Negishi-type cross-coupling reaction with arylzinc reagents under mild conditions.