630-95-5

Basic information

• Product Name: α,α-Diphenylnaphthalene-1-methanol
• Synonyms: Diphenyl-1-naphtylcarbinol;Diphenyl-1-naphtylmethanol;α-(1-Naphtyl)benzhydrol;α-(1-Naphtyl)benzhydryl alcohol;α,α-Diphenyl-1-naphthalenemethanol;α,α-Diphenylnaphthalene-1-methanol
• CAS NO: 630-95-5
• Molecular Formula: C₂₃H₁₈O
• Molecular Weight: 310.38842
• Mol File: 630-95-5.mol
• Article Data: 11

Chemical Properties

• Melting Point: 136.5°C
• Boiling Point: 410.55°C (rough estimate)
• Flash Point: 197.5°C
• Appearance: /
• Density: 1.0502 (rough estimate)
• Vapor Pressure: 8.49E-11mmHg at 25°C
• Refractive Index: 1.6380 (estimate)
• CAS DataBase Reference: α,α-Diphenylnaphthalene-1-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: α,α-Diphenylnaphthalene-1-methanol(630-95-5)
• EPA Substance Registry System: α,α-Diphenylnaphthalene-1-methanol(630-95-5)

Safety Data

• Hazardous Substances Data: 630-95-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C23H18O/c24-23(19-12-3-1-4-13-19,20-14-5-2-6-15-20)22-17-9-11-18-10-7-8-16-21(18)22/h1-17,24H

Upstream product

• 108-86-1 bromobenzene 
• 642-29-5 1-benzoylnaphthalene 
• 119-61-9 benzophenone 
• 90-11-9 1-Bromonaphthalene 
• 100-52-7 benzaldehyde 
• 60-29-7 diethyl ether 
• 71-43-2 benzene 
• 91-20-3 naphthalene 
• 763025-01-0 benzophenone radical anion potassium salt 
• 1204-50-8 sodium benzophenone ketyl 
• 741186-20-9 benzophenone radical anion lithium salt 
• 7601-90-3 perchloric acid 
• 75774-82-2 (1-naphthyl)diphenylmethylamine 
• 7664-93-9 sulfuric acid 

Downstream Products

• 15910-18-6 1-benzhydrylnaphthalene 
• 104601-29-8 11-phenylbenzofluorene 
• 127787-73-9 1-(chlorodiphenylmethyl)naphthalene 
• 95803-48-8 3-[1]naphthyl-3,3-diphenyl-propionic acid 
• 3178-23-2 dicyclohexylmethane 
• 91-17-8 decalin 
• 119-61-9 benzophenone 
• 82777-03-5 1-([1,1'-biphenyl]-4-yl)naphthalene 
• 27486-76-6 (R)-2-Amino-3-(naphthalen-1-yl-diphenyl-methylsulfanyl)-propionic acid 
• 760999-35-7 1,2-di-[1]naphthyl-1,1,2,2-tetraphenyl-ethane 
• 871887-25-1 1-(α-bromo-benzhydryl)-naphthalene 
• 75774-82-2 (1-naphthyl)diphenylmethylamine 
• 569673-92-3 2-[2-(1-naphthyl)phenyl]-2-propanol 
• 5925-58-6 (E)-1-(1-naphthyl)-1,2-diphenylethene 

Relevant articles and documents

(2-Ethylhexyl)sodium: A Hexane-Soluble Reagent for Br/Na-Exchanges and Directed Metalations in Continuous Flow

We report the on-demand generation of hexane-soluble (2-ethylhexyl)sodium (1) from 3-(chloromethyl)heptane (2) using a sodium-packed-bed reactor under continuous flow conditions. Thus, the resulting solution of 1 is free of elemental sodium and therefore suited for a range of synthetic applications. This new procedure avoids the storage of an alkylsodium and limits the handling of metallic sodium to a minimum. (2-Ethylhexyl)sodium (1) proved to be a very useful reagent and undergoes in-line Br/Na-exchanges as well as directed sodiations. The resulting arylsodium intermediates are subsequently trapped in batch with various electrophiles such as ketones, aldehydes, Weinreb-amides, imines, allyl bromides, disulfides and alkyl iodides. A reaction scale-up of the Br/Na-exchange using an in-line electrophile quench was also reported.

The absolute configuration of simple aliphatic alcohols through a chemical/computational approach: triarylether derivatives of (+)-endo-2-norborneol as a case study

The reliable determination of the absolute configuration of (+)-endo-2-norborneol 1, chosen as a representative case of simple aliphatic UV-vis transparent alcohols, was obtained by transforming this compound in its 1-naphthyl-diphenylmethyl ether 5 whose

Palladium-catalyzed arylation of α,α-disubstituted arylmethanols via cleavage of a C-C or a C-H bond to give biaryls

The palladium-catalyzed arylation of α,α-disubstituted arylmethanols with aryl halides proceeds not only via C-H bond cleavage at the ortho-position, but also via cleavage of the sp2-sp3 C-C bond with the liberation of ketones (β-carbon elimination) to give the corresponding biaryls. Both reactions appear to occur through common arylpalladium(II) alcoholate intermediates. The results of systematic studies with respect to which C-C or C-H bond is preferentially cleaved in the arylation are reported. Among the important findings is the selective elimination of ortho-substituted aryl groups even from aryl(diphenyl)methanols due to steric reasons. Thus, various biaryls having ortho-substituents can be produced efficiently by treatment of the corresponding aryl(diphenyl or dimethyl)methanols with aryl bromides and chlorides.