5925-66-6Relevant academic research and scientific papers
Synthesis and antiproliferative activity of novel selenoester derivatives
Domínguez-álvarez, Enrique,Plano, Daniel,Font, María,Calvo, Alfonso,Prior, Celia,Jacob, Claus,Palop, Juan Antonio,Sanmartín, Carmen
, p. 153 - 166 (2014)
A series of 31 new selenoesters were synthesized and their cytotoxic activity was evaluated against a prostate cancer cell line (PC-3). The most active compounds were also tested against three tumoural cell lines (MCF-7, A-549 and HT-29) and one non-tumou
Synthesis of selenol esters using acyl halides and a novel selenating reagent, LiAlHSeH
Koketsu, Mamoru,Asada, Hiroshi,Ishihara, Hideharu
, p. 591 - 595 (2007/10/03)
Several selenol esters were synthesized by the reaction of acyl chlorides with LiAlHSeH then with alkyl halides in moderate to good yields.
A Facile Preparation of Lithium Selenocarboxylates
Kojima, Yoshihiro,Ibi, Kazumasa,Kanda, Takahiro,Ishihara, Hideharu,Murai, Toshiaki,Kato, Shinzi
, p. 990 - 992 (2007/10/02)
A series of lithium selenocarboxylates 2 were synthesized in good yield by the direct reaction of acyl chlorides with lithium selenide.The salts 2 were soluble in ether and tetrahydrofuran and readily reacted with alkyl iodides to give the corresponding Se-alkyl esters in quantitative yields.
The invention of radical reactions. Part XXVII. Modified Julia synthesis of olefins using radical deoxygenation
Barton, Derek H. R.,Tachdjian, Catherine
, p. 7109 - 7120 (2007/10/02)
Xanthate derivatives of β-hydroxy sulfones react with methyl radicals generated from the photolysis of N-acetyloxy-2-thiopyridone to give the corresponding olefin. Under identical conditions a secondary alcohol is transformed into its thiopyridyl derivative.
Synthesis Utilizing Reducing Ability of Carbon Monoxide: A New Method for Selective Synthesis of Diorganyl Selenides and Diselenides Using a Selenium-Carbon Monoxide-Water Reaction System
Nishiyama, Yutaka,Katsuura, Akio,Negoro, Atsuhito,Hamanaka, Sawako,Miyoshi, Noritaka,et al.
, p. 3776 - 3780 (2007/10/02)
A new approach to the synthesis of diorganyl selenides and diselenides is described.Selective generation of tertiary amine salts of hydrogen selenide (->*+>) and hydrogen diselenide (->*+>) ha
DIMETHYLALUMINIUM METHANESELENOLATE - A USEFUL REAGENT FOR THE PREPARATION OF SELENOESTERS. A NEW FRIEDEL-CRAFTS ACYLATION PROCEDURE PROMOTED BY Cu(I)
Kozikowski, Alan P.,Ames, Anthony
, p. 4821 - 4834 (2007/10/02)
The preparation of a new aluminium reagent, dimethylaluminium methaneselenolate (Me2AlSeMe) is described.The reactivity of this aluminium reagent toward a variety of organic substrates has been studied.Me2AlSeMe will convert O-alkyl esters to selenoesters in high yield.These selenoesters function as extremely reactive acyl transfer agents and are converted to acids, esters, and amides on reaction with water, alcohols or amines in the presence of a selenophilic metal cation.The selenoesters will, moreover, acylate reactive arenes and heterocyclic compounds when cuprous triflate is employed as the selenophilic metal cation.This latter transformation constitutes a new transition metal promoted variant of the Friedel-Crafts acylation reaction.
The Preparation of (Methylthio)- and (Methylseleno)-tri(alkyl or aryl)phosphonium Salts and Their Reactions with Carboxylic Acids and Alcohols
Haynes, Richard K.,Indorato, Carlo
, p. 1183 - 1194 (2007/10/02)
A series of (methylthio)- and (methylseleno)-triphenylphosphonium salts and the analogous tributylphosphonium salts have been prepared by methylation of the corresponding tertiary phosphine sulfides and selenides.Details of their 1H, 13C and 31P n.m.r. spectra are given.Whereas the (methylthio)- and (methylseleno)-triphenylphosphonium salts undergo rapid decomposition in the presence of tertiary ammonium carboxylates or tertiary amines, the (methylthio)- and (methylseleno)-tributylphosphonium salts convert such carboxylates into methanethiol and methaneselenol estersin acceptable yields.A tris(dimethylamino)(methylthio)phosphonium salt, on the other hand, converts benzoate into methyl benzoate in quantitative yield.Inferior yields of (methylthio)- and (methylseleno)-alkanes are obtained from two primary alcohols and the tributylphosphonium salts.
