59291-72-4

Basic information

• Product Name: 4-Isoxazolecarboxylicacid,3-phenyl-,ethylester(7CI,9CI)
• Synonyms: 4-Isoxazolecarboxylicacid,3-phenyl-,ethylester(7CI,9CI);4-Isoxazolecarboxylic acid, 3-phenyl-, ethyl ester;3-phenyl-4-Isoxazolecarboxylic acid ethyl ester
• CAS NO: 59291-72-4
• Molecular Formula: C₁₂H₁₁NO₃
• Molecular Weight: 217.22
• Product Categories: ISOXAZOLE
• Mol File: 59291-72-4.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Isoxazolecarboxylicacid,3-phenyl-,ethylester(7CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Isoxazolecarboxylicacid,3-phenyl-,ethylester(7CI,9CI)(59291-72-4)
• EPA Substance Registry System: 4-Isoxazolecarboxylicacid,3-phenyl-,ethylester(7CI,9CI)(59291-72-4)

Safety Data

• Hazardous Substances Data: 59291-72-4(Hazardous Substances Data)

Upstream product

• 34780-29-5 3-oxo-propionic acid ethyl ester 
• 698-16-8 benzohydroximoyl chloride 
• 932-90-1 syn-benzaldehyde oxime 
• 924-99-2 ethyl 3-(dimethylamino)acrylate 
• 704-18-7 2-(hydroxyimino)-2-phenylacetic acid 
• 623-47-2 propynoic acid ethyl ester 

Downstream Products

• 18718-84-8 3-phenyl-4-isoxazolecarboxylic acid 

Relevant articles and documents

Hypervalent Iodine(III) Reagent Mediated Regioselective Cycloaddition of Aldoximes with Enaminones

An efficient oxidative cycloaddition of enaminones with nitrile oxides generated in situ from respective aldoximes using hypervalent iodine reagents has been developed. Reactions of various aldoximes with enaminones in the presence of [hydroxy(tosyloxy)iodo]benzene involved the regioselective cycloaddition reaction resulting in the formation of the 3,4-disubstituted isoxazoles in moderate to good yields. Structures of several isoxazole products were confirmed by a single X-ray crystallography.

Generation of nitrile oxides from oxime derivatives by the oxidation with ammonium hexanitratocerate(IV)

Aromatic and aliphatic nitrile oxides are generated by the oxidation of α-hydroxyimino carboxylic acid with ammonium hexanitratocerate(IV). They react with olefinic and acetylenic dipolarophiles to give the corresponding cycloaddition products in good yield. The oxidation of α-oxo aldoximes also affords α-oxo carbonitrile oxides.

3-Aryl-4-isoxazolecarboxylic acids as plant growth regulants

3-Aryl-4-isothiazolecarboxylic acids as well as 3-aryl-4-isoxazolecarboxylic acids have been found to be effective plant growth regulants especially when applied to soybean plants.