59291-87-1

Upstream product

• 108-73-6 3,5-dihydroxyphenol 
• 100-39-0 benzyl bromide 
• 2999-40-8 1,3,5-triacetoxybenzene 
• 116345-96-1 5-hydroxy-1,3-phenylene diacetate 
• 850399-67-6 1,3-di-O-acetyl-5-O-benzyl-benzophenone 

Downstream Products

• 156276-57-2 C₄₇H₆₀O₉ 
• 171369-22-5 1-Benzyloxy-3,5-bis-[3-(4-tert-butyl-phenoxy)-propoxy]-benzene 
• 188399-42-0 3-Benzyloxy-5-[(4S,5S)-5-(4-tert-butyl-phenoxymethyl)-2,2-dimethyl-[1,3]dioxolan-4-ylmethoxy]-phenol 
• 192379-04-7 17-Benzyloxy-2,5,8,11,14,20,23,26,29,32-decaoxa-tricyclo[31.2.2.1^15,19]octatriaconta-1⁽³⁶⁾,15,17,19⁽³⁸⁾,33⁽³⁷⁾,34-hexaene 
• 192379-03-6 17-Benzyloxy-2,5,8,11,14,20,23,26,29,32-decaoxa-tricyclo[31.3.1.1^15,19]octatriaconta-1⁽³⁷⁾,15,17,19⁽³⁸⁾,33,35-hexaene 
• 591767-49-6 bis(5-benzyloxy-1,3-phenylene)-26-crown-8 
• 591767-48-5 3,5-bis(9-chloro-1,4,7-trioxanonyl)benzyloxybenzene 
• 59434-20-7 1,3,5-tri-O-benzylphloroglucinol 
• 249925-35-7 C₄₂H₅₂O₁₂ 
• 908864-77-7 trifluoro-methanesulfonic acid 5-benzyloxy-3-hydroxy-2-iodo-phenyl ester 
• 908864-79-9 4-benzyloxy-8-(tert-butyl-dimethyl-silanyloxy)-7,7,8-trimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-2-ol 
• 908864-71-1 trifluoro-methanesulfonic acid 5-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-2-iodo-phenyl ester 
• 908864-76-6 trifluoro-methanesulfonic acid 5-benzyloxy-2-iodo-3-trifluoromethanesulfonyloxy-phenyl ester 
• 908864-80-2 4-benzyloxy-3,5-dibromo-8-(tert-butyl-dimethyl-silanyloxy)-7,7,8-trimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-2-ol 

Relevant academic research and scientific papers

Fibrinogen receptor antagonists and their use

This invention relates to novel fused bicyclic compounds of the general formula (I): wherein the symbols are defined herein, to pharmaceutical compositions containing the compounds, processes for preparing the compounds, and to methods of using the compounds, alone or in combination with other therapeutic agents. The compounds are antagonists of the platelet glycoprotein IIb/IIIa fibrinogen receptor complex, and are therefore useful for the inhibition of platelet aggregation, and for the treatment of thrombotic diseases and other diseases.

Dodecamethoxy- and hexaoxotricyclobutabenzene: Synthesis and characterization

We report herein the syntheses of dodecamethoxytricyclobutabenzene (TCBB) 1 and hexaoxo-TCBB 2, a class of molecules with structural and theoretical interest. The preparation is based on the 3-fold [2 + 2] cycloadditions of benzyne and ketene silyl acetal

FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE

This invention relates to novel fused bicyclic compounds of the general formula (I): wherein the symbols are defined herein, to pharmaceutical compositions containing the compounds, processes for preparing the compounds, and to methods of using the compounds, alone or in combination with other therapeutic agents. The compounds are antagonists of the platelet glycoprotein IIb/IIIa fibrinogen receptor complex, and are therefore useful for the inhibition of platelet aggregation, and for the treatment of thrombotic diseases and other diseases.

First pseudorotaxane-like [3]complexes based on cryptands and paraquat: Self-assembly and crystal structures

A new cryptand, bis(1,3,5-phenylene)tri(1,4,7,10-tetraoxadecyl) (3a), has been synthesized in good yield from bis(5-hydroxy-1,3-phenylene)-26-crown-8 (2a) and tri(ethylene glycol) ditosylate using pseudo-high dilution conditions. 3a forms a strong 1:1 complex with paraquat (1) in acetone solution with a high apparent association constant, 1.4 × 104 M-1. A stoichiometry of 1:1 was also observed by mass spectrometry in the gaseous state. However, in the solid state, as determined by X-ray crystallography, the two complexes of 3a and the previously reported homologous cryptand, bis(1,3,5-phenylene)tri(1,4,7,10,13-pentaoxatridecyl) (3b), with paraquat (1) have 2:1 stoichiometry. A unique feature of these trimolecular pseudorotaxane-like complexes is that the guest occupies parts of the cavities of two cryptand molecules. For the first time it was found that in cryptand-based complexes, different stoichiometries are possible for the same host-guest pair.