59337-94-9

Basic information

• Product Name: thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide(SALTDATA: FREE)
• Synonyms: thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide(SALTDATA: FREE);1,1-diketothieno[2,3-d]isothiazol-3-one;1,1-dioxo-3-thieno[2,3-d]isothiazolone;1,1-dioxothieno[2,3-d][1,2]thiazol-3-one;1,1-dioxothieno[2,3-d]isothiazol-3-one;sodium thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide;1,1-dioxothieno[2,3-d][1,2]thiazol-3-olate
• CAS NO: 59337-94-9
• Molecular Formula: C5H3NO3S2
• Molecular Weight: 189.21222
• Mol File: 59337-94-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide(SALTDATA: FREE)(CAS DataBase Reference)
• NIST Chemistry Reference: thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide(SALTDATA: FREE)(59337-94-9)
• EPA Substance Registry System: thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide(SALTDATA: FREE)(59337-94-9)

Safety Data

• Hazardous Substances Data: 59337-94-9(Hazardous Substances Data)

Usage

Uses

2,3-Dihydro-3-oxothieno[2,3-d]isothiazole 1,1-Dioxide is used as a reactant in the synthesis of 3-(azol-1-yl)thienoisothiazole 1,1-dioxides.

Upstream product

• 59337-78-9 4-(aminosulfonyl)-3-thiophenecarboxylic acid methyl ester 
• 59337-97-2 3-sulfamoylthiophene-2-carboxylic acid 
• 59337-98-3 3-(N-tert-butylsulfamoyl)-thiophene-2-carboxylic acid 
• 59337-92-7 2-(carbomethoxy)thiophene-3-sulfonyl chloride 
• 22288-78-4 Methyl 3-aminothiophene-2-carboxylate 
• 59337-93-8 Methyl 3-sulfamoylthiophene-2-carboxylate 

Downstream Products

• 113387-66-9 3-Pyrazol-1-yl-thieno[2,3-d]isothiazole 1,1-dioxide 
• 113387-68-1 3-(3,5-Dimethyl-pyrazol-1-yl)-thieno[2,3-d]isothiazole 1,1-dioxide 
• 113387-69-2 3-(4-Chloro-3,5-dimethyl-pyrazol-1-yl)-thieno[2,3-d]isothiazole 1,1-dioxide 
• 119120-83-1 1-(1,1-Dioxo-1H-1λ⁶-thieno[2,3-d]isothiazol-3-yl)-1H-benzotriazole 
• 59804-25-0 4-hydroxy-3-methoxycarbonyl-2-methyl-2H-thieno[2,3-e]-1,2-thiazine,1,1-dioxide 
• 98827-44-2 methyl 4-hydroxy-2H-thieno<2,3-e>-1,2-thiazine-3-carboxylate 1,1-dioxide 
• 94040-09-2 2,3-Dihydro-2-methyl-3-oxo-thieno<2,3-d>isothiazol-1,1-dioxid 
• 113387-70-5 1-(1,1-Dioxo-1H-1λ⁶-thieno[2,3-d]isothiazol-3-yl)-1H-indazole 
• 113387-67-0 3-(4-Chloro-pyrazol-1-yl)-thieno[2,3-d]isothiazole 1,1-dioxide 

Relevant articles and documents

AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS

The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.

Thiophene isosteres: synthesis and pharmacological study of 3-(azol-1-yl)thieno isothiazole-1,1-dioxides

Three series of new 3-(azol-1-yl)thieno isothiazole-1,1-dioxides were synthesized and tested for anti-inflammatory and related pharmacological activities as well as for acute toxicity.Acetylsalicylic acid was used as the reference standard.Keywords - 3-(a