5937-24-6

Upstream product

• 141-97-9 ethyl acetoacetate 
• 459-57-4 4-fluorobenzaldehyde 
• 57-13-6 urea 
• 352-11-4 1-chloromethyl-4-fluorobenzene 
• 21351-39-3 monocarbamide dihydrogen sulfate 
• 459-56-3 4-fluorobenzylic alcohol 
• 24133-58-2 1,2-bis(4-fluorophenyl)-1,2-ethanediol 

Downstream Products

• 1091909-58-8 4-(4-fluorophenyl)-2-hydroxy-6-methylpyrimidine-5-carboxylic acid ethyl ester 
• 1296205-12-3 ethyl 1-(ethoxymethyl)-6-(4-fluorophenyl)-4-methyl-2-oxo-1,2,3,6-tetrahydropyrimidine-5-carboxylate 
• 1091909-58-8 ethyl 4-(4-fluorophenyl)-1,2-dihydro-6-methyl-2-oxopyrimidine-5-carboxylate 
• 854019-24-2 ethyl (S)-4-(4-fluorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 
• 854019-23-1 ethyl (R)-4-(4-fluorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 
• 1448024-48-3 (E)-ethyl 3-cinnamyl-4-(4-fluorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 
• 1448024-57-4 (E)-ethyl 4-(4-fluorophenyl)-6-methyl-2-oxo-3-(3-p-tolylallyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate 
• 1417542-50-7 ethyl 6-methyl-2-oxo-4-(4-flourophenyl)-3-[(4-phenyl-1H-1,2,3-triazol-1-yl)-methyl]-1,2,3,4-tetrahydropyrimidine-5-carboxylate 
• 1245716-52-2 ethyl 4-(4-fluorophenyl)-6-methyl-2-(tosyloxy)pyrimidine-5-carboxylate 
• 1448992-24-2 ethyl 4-(4-fluorophenyl)-2-(4-((7-chloroquinolin-4-yl)amino)butylamino)-6-methylpyrimidine-5-carboxylate 
• 1448992-18-4 2-chloro-4-(4-fluorophenyl)-6-methylpyrimidine-5-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Magnetic Silica-Coated Picolylamine Copper Complex [Fe3O4@SiO2@GP/Picolylamine-Cu(II)]-Catalyzed Biginelli Annulation Reaction

An efficient and heterogeneous novel magnetic silica-coated picolylaminecopper complex [Fe3O4@SiO2@GP/Picolylamine-Cu(II)] was synthesized, characterized, and employed as a magnetically recoverable nanocatalyst in Biginelli condensation for the preparatio

Fabrication of porous ultrathin carbon nitride nanosheet catalysts with enhanced photocatalytic activity for N- And O-heterocyclic compound synthesis

A simple and efficient photocatalytic method for the synthesis of dihydropyrimidinones (DHPMs) and their derivatives via porous ultrathin carbon nitride nanosheets (p-CNNs) without solvents was demonstrated. The yields of 3,4-dihydropyrimidin-2(1H)-ones/t

RETRACTED ARTICLE: Boric acid in magnetized water: Clean and powerful media for synthesis of 3,4-dihydropyrimidin-2(1: H)-ones

Water was magnetized via an external magnetic field and employed, for the first time, as a solvent in green preparation of 3,4-dihydropyrimidin-2(1H)-ones by the one-pot three-component condensation reaction using boric acid as a catalyst. Shorter reactio

Tungsten-substituted molybdophosphoric acid impregnated with kaolin: effective catalysts for the synthesis of 3,4-dihydropyrimidin-2(1: H)-ones v i a biginelli reaction

A series of highly reusable heterogeneous catalysts (10-25 wt% PMo7W5/kaolin), consisting of tungsten-substituted molybdophosphoric acid, H3PMo7W5O40·24H2O (PMo7W5) impregnated with acid treated kaolin clay was synthesized by the wetness impregnation meth

Synthesis method of dihydropyrimidinone compound

The invention discloses a synthesis method of a dihydropyrimidone compound, which belongs to the technical field of organic synthesis, and comprises the following steps: by taking benzaldehyde or a derivative thereof, ethyl acetoacetate or acetylacetone a

A Set of phenyl sulfonate metal coordination complexes triggered Biginelli reaction for the high efficient synthesis of 3,4-dihydropyrimidin-2(1H)-ones under solvent-free conditions

Three new metal coordination complexes, namely, [Co (DPE)(H2O)4](DPE)(BS)2 (1), [Co (DPE)2(H2O)4](ABS)2 (2), [Co (DPE)(H2O)4](MBS)2(CH3/sub

Natural dolomitic limestone-catalyzed synthesis of benzimidazoles, dihydropyrimidinones, and highly substituted pyridines under ultrasound irradiation

Natural dolomitic limestone (NDL) is employed as a heterogeneous green catalyst for the synthesis of medicinally valuable benzimidazoles, dihydropyrimidinones, and highly functionalized pyridines via C–N, C–C, and C–S bond formations in a mixture of ethan

An efficient and recyclable L-proline triflate ionic liquid catalyst for one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones via the multi-component Biginelli reaction

A simple, efficient, and environmentally-friendly process has been developed for the synthesis of L-proline triflate ionic liquid (L-ProTfO) from L-proline and triflic acid using ultrasound irradiation. The combination of L-proline triflate ionic liquid t

Synthesis, cytotoxic assessment, and molecular docking studies of 2,6-diaryl-substituted pyridine and 3,4-dihydropyrimidine-2(1H)-one scaffolds

Cancer is one of the main global health problems. In order to develop novel antitumor agents, we synthesized 3,4-dihydropyrimidine-2(1H)-one (DHPM) and 2,6-diaryl-substituted pyridine derivatives as potential antitumor structures and evaluated their cytot

Efficient biocatalytic strategy for one-pot Biginelli reaction via enhanced specific effects of microwave in a circulating reactor

A one-pot efficient biocatalytic strategy for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones was developed in a circulating microwave reactor selecting α-chymotrypsin as the promiscuous biocatalyst. In the circulating reaction system, the combination o