59409-41-5

Basic information

• Product Name: N-ALPHA-LAUROYL-L-LYSINE
• Synonyms: N-ALPHA-LAUROYL-L-LYSINE;N-LAUROYL-L-LYSINE;N2-(1-oxododecyl)-L-lysine;N(ALPHA)-LAUROYL-L-LYSINE 99+%;Einecs 261-742-0
• CAS NO: 59409-41-5
• Molecular Formula: C₁₈H₃₆N₂O₃
• Molecular Weight: 328.49
• EINECS: 261-742-0
• Product Categories: Amino Acids;I - Z;Modified Amino Acids
• Mol File: 59409-41-5.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 526 °C at 760 mmHg
• Flash Point: 271.9 °C
• Appearance: /
• Density: 0.994 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.482
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-ALPHA-LAUROYL-L-LYSINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-ALPHA-LAUROYL-L-LYSINE(59409-41-5)
• EPA Substance Registry System: N-ALPHA-LAUROYL-L-LYSINE(59409-41-5)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 3-10
• Hazardous Substances Data: 59409-41-5(Hazardous Substances Data)

Usage

General Description

N-Alpha-Lauroyl-L-Lysine is a compound derived from the amino acid lysine and lauric acid. It is commonly used in the cosmetic and personal care industry as a surfactant, emulsifier, and conditioning agent. This chemical is known for its ability to improve the foaming and cleansing properties of personal care products, such as shampoos, body washes, and facial cleansers. N-Alpha-Lauroyl-L-Lysine is also valued for its moisturizing and conditioning properties, making it a popular ingredient in hair care products and skincare formulations. Additionally, it is considered to be a mild and gentle ingredient, making it suitable for sensitive skin types.

InChI:InChI=1/C18H36N2O3/c1-2-3-4-5-6-7-8-9-10-14-17(21)20-16(18(22)23)13-11-12-15-19/h16H,2-15,19H2,1H3,(H,20,21)(H,22,23)/t16-/m0/s1

Upstream product

• 112-16-3 n-dodecanoyl chloride 
• 16079-52-0 sodium salt of L-lysine 
• 143-07-7 lauric acid 
• 56-87-1 L-lysine 
• 2418-95-3 (S)-2-amino-6-(tert-butoxycarbonylamino)hexanoic acid 
• 609819-28-5 N-2-dodecanoyl-N-6-tert-butoxycarbonyl-L-lysine 
• 14511-39-8 2(S)-2-amino-6-(benzylideneamino)hexanoic acid 
• 1155-64-2 N₆-[(benzyloxy)carbonyl]-L-lysine 
• 111-82-0 methyl n-dodecanoate 

Downstream Products

• 143-07-7 lauric acid 
• 56-87-1 L-lysine 
• 14379-54-5 N^α,N^ε-bis(1-oxododecyl)-L-lysine 
• 1391999-27-1 N_α-lauroyl-N_ε-isothiocyanato-L-lysine 

Relevant articles and documents

Preparation method of epsilon-N lauroyl lysine

The invention relates to a preparation method of epsilon-N lauroyl lysine. According to the preparation method, lysine or lysine salt and lauroyl chloride are used as raw materials. The method comprises the following specific steps: dissolving lysine in methanol to obtain a lysine methanol solution, dropwise adding lauroyl chloride at a certain temperature for an amidation reaction of lysine methanol solution, and adjusting the pH value of the mixed solution until the pH value is greater than 7 and less than or equal to 11; and after the reaction is finished, adjusting the pH value of the mixed solution to 7-9, and carrying out washing with methanol and an alcohol-water mixed solution sequentially to obtain a high-purity product. Compared with the prior art, the preparation method has theadvantages that only one step is needed for synthesis, subsequent treatment steps are simple, high temperature and high pressure are not needed in the reaction, a reaction solvent can be distilled, recovered and recycled, and the obtained product has high purity and good industrial production potential.

Using the ionic liquid amino or N-acylated peptide dialkylsulfosuccinic N of manufacturing method

PROBLEM TO BE SOLVED: To provide a method for synthesizing N-acylamino acid or N-acylpeptide without using fatty acid chloride.SOLUTION: The method for producing N-acylamino acid or N-acylpeptide comprises a step of reacting ionic liquefied amino acid or peptide (A) with a fatty acid or ester thereof (B) under such a condition that a molar ratio of (A):(B) is 1:10 to 10:1.

A novel acylase from Streptomyces mobaraensis that efficiently catalyzes hydrolysis/synthesis of capsaicins as well as N-acyl-L-amino acids and N-acyl-peptides

A novel enzyme that catalyzes efficient hydrolysis of capsaicin (8-methyl-N-vanillyl-6-nonenamide) was isolated from the culture broth of Streptomyces mobaraensis. The enzyme consisted of two dissimilar subunits with molecular masses of 61 and 19 KDa. The enzyme was activated and stabilized in the presence of Co2+. It showed a pH optimum of about 8 and was stable at temperatures of up to 55°C for 1 h at pH 7.8. The specific activity of the enzyme for the hydrolysis of capsaicin was 10 2-104 times higher than those for the enzymes reported to date. In an aqueous/n-hexane biphasic system, capsaicin analogues such as octanoyl, decanoyl, and lauroyl vanillylamides were synthesized from the corresponding fatty acids and vanillylamine at yields of 50% or greater. In addition, the enzyme catalyzed the deacylation of N-lauroyl-L-amino acids and N-lauroyl-L-dipeptides and the efficient synthesis of Nα-lauroyl-L-lysine, Nε-lauroyl-L-lysine, and various N-lauroyl-peptides in aqueous solution in both the absence and the presence of glycerol.