35350-37-9

Basic information

• Product Name: methyl 4-(4-methoxycarbonyl-2-nitro-phenyl)disulfanyl-3-nitro-benzoate
• CAS NO: 35350-37-9
• Molecular Formula: C₁₆H₁₂N₂O₈S₂
• Molecular Weight: 424.412
• Mol File: 35350-37-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 573.2°Cat760mmHg
• Flash Point: 300.5°C
• Density: 1.56g/cm³
• CAS DataBase Reference: methyl 4-(4-methoxycarbonyl-2-nitro-phenyl)disulfanyl-3-nitro-benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(4-methoxycarbonyl-2-nitro-phenyl)disulfanyl-3-nitro-benzoate(35350-37-9)
• EPA Substance Registry System: methyl 4-(4-methoxycarbonyl-2-nitro-phenyl)disulfanyl-3-nitro-benzoate(35350-37-9)

Safety Data

• Hazardous Substances Data: 35350-37-9(Hazardous Substances Data)

Upstream product

• 14719-83-6 methyl 3-nitro-4-chlorobenzoate 
• 2363-16-8 methyl 4-bromo-3-nitrobenzoate 
• 74-11-3 para-chlorobenzoic acid 
• 96-99-1 4-chloro-3-nitrobenzoate 
• 186581-53-3 diazomethane 
• 49706-71-0 bis(2-nitro-4-carboxyphenyl) disulfide 

Downstream Products

• 59515-34-3 4-mercapto-3-nitro-benzoic acid methyl ester 
• 59515-36-5 Methyl-3-nitro-4-chlorsulfenyl-benzoat 
• 478169-65-2 methyl 1,3-benzothiazole-5-carboxylate 
• 23616-15-1 methyl benzo[d][1,2,3]thiadiazole-5-carboxylate 
• 68867-17-4 1,3-benzothiazole-5-carboxylic acid 
• 32770-98-2 2-methyl-5-benzothiazolecarxylic acid methyl ester 
• 78822-61-4 Bis<2-amino-4-(carbomethoxy)phenyl>disulfide 
• 20061-46-5 2-methyl-1,3-benzothiazole-5-carbaldehyde 
• 32770-97-1 (2-methyl-1,3-benzothiazol-5-yl)methanol 

Relevant articles and documents

PYRAZOLOPYRIDINE PYRAZOLOPYRIMIDINE AND RELATED COMPOUNDS

In one aspect this invention relates generally to compounds of Formula: and sub-formulas thereof, or a tautomer of each thereof, a pharmaceutically acceptable salt of each thereof, or a pharmaceutically acceptable solvate of each of the foregoing, where X1, L1, L3, and R3 are described herein.

Design, synthesis, structure-activity relationship, and in vivo activity of azabicyclic aryl amides as α7 nicotinic acetylcholine receptor agonists

A novel set of azabicyclic aryl amides have been identified as potent and selective agonists of the α7 nAChR. A two-pronged approach was taken to improve the potential hERG liability of previously disclosed α7 nAChR agonist, PNU-282,987, while maintaining the compound's other desirable pharmacological properties. The first approach involved further exploration of the aryl carboxylic acid fragment of PNU-282,987, while the second approach focused on modification of the azabicyclic amine portion of PNU-282,987. The best compounds from each series are characterized by rapid brain penetration, good oral bioavailability in rat, and demonstrate in vivo efficacy in a rat P50 auditory sensory gating assay. At least one analog from each series (1h, 1o, 2a, 9a, and 18a) shows an improved hERG safety profile over PNU-282,987.

Synthesis of a new spiropyran based on [60]fullerene unit

A new compound 2: spiropyran with [60]fullerene unit was synthesized and characterized by FT-IR, MALDI-TOF MS, NMR, and UV-Vis spectra.