59530-33-5

Upstream product

• 87-86-5 Pentachlorophenol 
• 10026-13-8 phosphorus pentachloride 
• 2613-89-0 phenylmalonic acid 
• 83-13-6 diethyl 2-phenylmalonate 
• 101-97-3 Ethyl 2-phenylethanoate 
• 140-29-4 phenylacetonitrile 
• 7147-33-3 2-oxo-3-phenylbutanedioic acid diethyl ester 
• 37818-48-7 2-Phenyl-propanedioyl dichloride 

Downstream Products

• 120537-75-9 2-hydroxy-6-methyl-4-oxo-3-phenyl-4H-pyrido<1,2-a>pyrimidine 
• 1309477-15-3 C₃₁H₃₄N₂O₂ 
• 1309477-17-5 C₃₃H₃₈N₂O₂ 
• 1309477-19-7 C₃₅H₄₂N₂O₂ 
• 1309477-21-1 C₃₇H₄₆N₂O₂ 
• 1309477-23-3 C₃₉H₅₀N₂O₂ 
• 56431-38-0 3,6-Dihydro-1,2,3,5-tetraphenyl-1-pyrimidinium-4-olat 
• 120537-72-6 7-methyl-3-nitro-2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-1,8-naphthyridine 
• 120537-71-5 3-chloro-7-methyl-2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-1,8-naphthyridine 
• 108618-40-2 1,2-dihydro-4-hydroxy-7-methyl-2-oxo-3-phenyl-1,8-naphthyridine 

Relevant academic research and scientific papers

Total synthesis of monocyclic pyrimidinium betaines with fatty alkyl chains

Seven betaines were prepared by condensation of N,N'-diphenylamidines with malonic acid derivatives. The amidines were made via a multistep synthesis, starting from their corresponding fatty acids. Malonyl chloride and dipentachlorophenyl phenylmalonate, two derivatives of malonic acid, were obtained from malonic acid and benzyl chloride, respectively. Most of the products were characterized by IR, UV, 1H and 13C NMR. Biological assays of the synthesized betaines revealed their good antibacterial and antifungal activities against the Pseudomonas aeruginosa, Bacillus subtilis and Mucor ramannianus and an activity against Candida albicans.

Malonic esters

A compound of the formula I: STR1 wherein: R is substituted or unsubstituted C1-6 alkyl, a substituted or unsubstituted aromatic ring, a heterocyclic ring, a cycloalkyl group or a fused ring system, R1 is hydrogen, lower alkyl, cycloaliphatic or heterocyclic ring, and X is a halogen atom.