92486-65-2

Basic information

• Product Name: (3R,4R)-Diethyl1-benzylpyrrolidine-3,4-dicarboxylate
• Synonyms: (3R,4R)-Diethyl1-benzylpyrrolidine-3,4-dicarboxylate;Diethyl (3R,4R)-1-benzylpyrrolidine-3,4-dicarboxylate;(3R,4R)-1-Benzyl-pyrrolidine-3,4-dicarboxylic acid diethyl ester RACEMATE
• CAS NO: 92486-65-2
• Molecular Formula: C₁₇H₂₃NO₄
• Molecular Weight: 305.38
• Mol File: 92486-65-2.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (3R,4R)-Diethyl1-benzylpyrrolidine-3,4-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4R)-Diethyl1-benzylpyrrolidine-3,4-dicarboxylate(92486-65-2)
• EPA Substance Registry System: (3R,4R)-Diethyl1-benzylpyrrolidine-3,4-dicarboxylate(92486-65-2)

Safety Data

• Hazardous Substances Data: 92486-65-2(Hazardous Substances Data)

Usage

General Description

(3R,4R)-Diethyl1-benzylpyrrolidine-3,4-dicarboxylate is a chemical compound with a molecular formula of C19H25NO4. It is a pyrrolidine derivative with two ethyl groups and a benzyl group attached to the pyrrolidine ring, as well as carboxylate groups at the 3 and 4 positions. (3R,4R)-Diethyl1-benzylpyrrolidine-3,4-dicarboxylate is often used as a building block in the synthesis of pharmaceuticals and other organic compounds. It has potential applications in drug discovery and development, particularly in the design of novel therapeutic agents for various medical conditions. Additionally, (3R,4R)-Diethyl1-benzylpyrrolidine-3,4-dicarboxylate has been studied for its pharmacological activities and may have potential as a drug candidate for further research and development.

Upstream product

• 79909-16-3 1,4-Bis(ethoxy)-1,4-bis(trimethylsiloxy)-1,3-butadien 
• 92486-61-8 Benzyl-bis-methylsulfanylmethyl-amine 
• 50-00-0 formaldehyd 
• 17136-36-6 N-benzylglycine 
• 623-91-6 diethyl Fumarate 
• 53215-95-5 N-(trimethylsilylmethyl)benzylamine 
• 93102-05-7 N-benzyl-N-(methoxymethyl)-N-[(trimethylsilyl)methyl]amine 

Downstream Products

• 865451-74-7 (3R,4R)-4-[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)phenylcarbamoyl]pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester 
• 1212409-03-4 ((3SR,4SR)-1-tert-butoxycarbonyl)4-(ethoxycarbonyl)pyrrolidine-3-carboxylic acid 
• 595556-31-3 (R,R)-pyrrolidine-1,3,4-tricarboxylic acid 1-tert-butyl ester 3-ethyl ester 
• 595547-21-0 ethyl (3S,4S)-N-Boc-pyrrolidine-3,4-dicarboxylate 
• 1782350-51-9 (3S,4S)-1-(tert-butoxycarbonyl)pyrrolidine-3,4-dicarboxylic acid 
• 3919-43-5 1-benzyl-pyrrole-3,4-dicarboxylic acid diethyl ester 

Relevant articles and documents

[3+2] Dipolar cycloadditions of an unstabilised azomethine ylide under continuous flow conditions

The [3+2] dipolar cycloaddition reactions of the unstabilised azomethine ylide precursor benzyl(methoxymethyl)(trimethylsilylmethyl)amine with 12 electron-deficient alkenes in the presence of catalytic trifluoroacetic acid are examined under continuous fl

NEW SOLID FORMS OF FXA INHIBITORS

The invention is concerned with crystalline forms or amorphous forms of a pyrrolidine- 3,4-dicarboxamide derivative, which is useful as an active ingredient of medicaments for the diseases which can be treated by the coagulation factor Xa inhibitors.

Chemoenzymatic preparation of non-racemic N-Boc-pyrrolidine-3,4-dicarboxylic acid 3-ethyl esters and their 4-hydroxymethyl derivatives

For the synthesis of metalloproteinase inhibitors the (R,R)- and (S,S)-monoethyl esters of N-Boc-pyrrolidine-3,4-dicarboxylic acid were prepared as key intermediates from the trans-diester racemate by two consecutive, highly selective enzymatic reactions.