92486-65-2

Usage

Uses

Used in Pharmaceutical Synthesis:
(3R,4R)-Diethyl1-benzylpyrrolidine-3,4-dicarboxylate is used as a key building block for the synthesis of various pharmaceuticals and organic compounds. Its unique structure allows for the creation of novel therapeutic agents that can address a range of medical conditions.
Used in Drug Discovery and Development:
In the field of drug discovery and development, (3R,4R)-Diethyl1-benzylpyrrolidine-3,4-dicarboxylate serves as a promising candidate for the design of new drugs. Its pharmacological activities are of interest to researchers, who are exploring its potential as a precursor to develop effective treatments for various diseases.
Used in Research and Development of Therapeutic Agents:
(3R,4R)-Diethyl1-benzylpyrrolidine-3,4-dicarboxylate is utilized in research and development efforts to create therapeutic agents. Its role in the synthesis of potential drug candidates is crucial, as it can contribute to the advancement of medicine by providing new options for treatment.
Used in the Design of Novel Medical Treatments:
(3R,4R)-Diethyl1-benzylpyrrolidine-3,4-dicarboxylate is also used in the design of novel medical treatments, where its unique properties can be leveraged to develop innovative solutions for various health issues. Its potential as a drug candidate is currently under investigation, which may lead to its application in future medical therapies.

Upstream product

• 50-00-0 formaldehyd 
• 17136-36-6 N-benzylglycine 
• 623-91-6 diethyl Fumarate 
• 93102-05-7 N-benzyl-N-(methoxymethyl)-N-[(trimethylsilyl)methyl]amine 
• 53215-95-5 N-(trimethylsilylmethyl)benzylamine 
• 79909-16-3 1,4-Bis(ethoxy)-1,4-bis(trimethylsiloxy)-1,3-butadien 
• 92486-61-8 Benzyl-bis-methylsulfanylmethyl-amine 

Downstream Products

• 865451-74-7 (3R,4R)-4-[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)phenylcarbamoyl]pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester 
• 1212409-03-4 ((3SR,4SR)-1-tert-butoxycarbonyl)4-(ethoxycarbonyl)pyrrolidine-3-carboxylic acid 
• 595556-31-3 (R,R)-pyrrolidine-1,3,4-tricarboxylic acid 1-tert-butyl ester 3-ethyl ester 
• 595547-21-0 ethyl (3S,4S)-N-Boc-pyrrolidine-3,4-dicarboxylate 
• 1782350-51-9 (3S,4S)-1-(tert-butoxycarbonyl)pyrrolidine-3,4-dicarboxylic acid 
• 3919-43-5 1-benzyl-pyrrole-3,4-dicarboxylic acid diethyl ester 

Relevant academic research and scientific papers

[3+2] Dipolar cycloadditions of an unstabilised azomethine ylide under continuous flow conditions

The [3+2] dipolar cycloaddition reactions of the unstabilised azomethine ylide precursor benzyl(methoxymethyl)(trimethylsilylmethyl)amine with 12 electron-deficient alkenes in the presence of catalytic trifluoroacetic acid are examined under continuous fl

PROCESSES FOR THE PREPARATION OF (3R, 4R) -N- (4 -CHLOROPHENYL) -1- (2, 2-DIFLUOROETHYL) -N' - [2-FLUORO-4- (2-OXO-1 (2H) -PYRIDINYL) PHENYL] -3, 4-PYRROLIDINEDICARBOXAMIDE

The invention is concerned with processes for the manufacture of pyrrolidine-3,4- dicarboxamide derivative of formula (I), and the intermediates useful for those processes.

NEW SOLID FORMS OF FXA INHIBITORS

The invention is concerned with crystalline forms or amorphous forms of a pyrrolidine- 3,4-dicarboxamide derivative, which is useful as an active ingredient of medicaments for the diseases which can be treated by the coagulation factor Xa inhibitors.

NOVEL PYRROLIDINE-3,4-DICARBOXAMIDE DERIVATIVES

The invention is concerned with novel pyrrolidine-3,4-dicarboxamide derivatives of Formula (I) ; wherein Rl to R9 and X are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These c

Chemoenzymatic preparation of non-racemic N-Boc-pyrrolidine-3,4-dicarboxylic acid 3-ethyl esters and their 4-hydroxymethyl derivatives

For the synthesis of metalloproteinase inhibitors the (R,R)- and (S,S)-monoethyl esters of N-Boc-pyrrolidine-3,4-dicarboxylic acid were prepared as key intermediates from the trans-diester racemate by two consecutive, highly selective enzymatic reactions.

TRIMETHYLSILYL TRIFLATE-CATALYZED REACTION OF BIS(METHYLTHIOMETHYL)AMINES WITH DIKETENE SILYL ACETALS. NOVEL CYCLIZATION LEADING TO FIVE- TO SEVEN-MEMBERED ALICYCLIC AMINES

Bis(methylthiomethyl)amines have been shown to react with diketene silyl acetals in the presence of trimethylsilyl triflate catalyst to give five- to seven-membered alicyclic amines.