595568-56-2

Upstream product

• 150966-64-6 2-(tert-butyldimethylsiloxymethyl)-4-(2,4,6-triisoporpyl-benzenesulfonyl-hydrazono)-1,3,3-trimethyl-cyclohex-1-ene 
• 150966-63-5 3-(tert-butyldimethylsiloxymethyl)-2,2,4-trimethyl-cyclohex-3-ene-1-one 
• 150966-81-7 6,6,8-trimethyl-1,4-dioxaspiro[4.5]decan-7-one hydrazone 
• 150966-58-8 5,5-(ethylenedioxy)-2,,6,6-trimethyl-1-iodocyclohexene 
• 14782-52-6 ethylene glycole monoacetal of 2,2-dimethylcyclohexane-1,3-dione 
• 141665-47-6 5,5-(ethylenedioxy)-2,6,6-trimethyl-1-cyclohexenecarboxaldehyde 
• 114198-58-2 3,3-(ethylenedioxy)-2,2,6-trimethyl-1-cyclohexanone 
• 152328-14-8 3-Hydroxymethyl-2,2,4-trimethyl-cyclohex-3-enone 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 562-13-0 2,2-dimethyl-1,3-cyclohexanedione 
• 595568-54-0 2-(tert-butyldimethylsiloxymethyl)-4-hydroxymethyl-1,3,3-trimethyl-cyclohexa-1,4-diene 

Downstream Products

• 595568-53-9 (4S,5R)-2-(tert-butyldimethylsiloxymethyl)-4,6-dihydroxy-4-benzoyloxymethyl-1,3,3-trimethyl-cyclohex-1-ene 
• 595568-59-5 (4S)-2-(tert-butyldimethylsiloxymethyl)-4,6-dihydroxy-4-benzoyloxymethyl-1,3,3-trimethyl-cyclohex-1-ene 
• 595568-60-8 (5S)-3-(tert-butyldimethylsiloxymethyl)-5-hydroxy-5-benzoyloxymethyl-2,4,4-trimethyl-cyclohex-2-en-1-one 

Relevant academic research and scientific papers

A concise enantioselective synthesis of a fully oxygen substituted ring A taxol precursor

A concise synthesis of the oxygen substituted ring A compound 2 found in Taxol 1a and Taxotere 1b starting from 2,2-dimethylcyclohexane-1,3-dione and proceeding via the key intermediates 8 and 11, is described. The absolute configuration of 2 was established from an X-ray crystal structure determination of a 4-bromophenylbenzoate derivative, viz. 15.