596103-17-2

Basic information

• Product Name: Adenosine, 2-chloro-N-methyl-2',3'-O-(1-methylethylidene)-4'-thio-
• CAS NO: 596103-17-2
• Molecular Formula: C14H18ClN5O3S
• Molecular Weight: 371.848
• Mol File: 596103-17-2.mol

Chemical Properties

• CAS DataBase Reference: Adenosine, 2-chloro-N-methyl-2',3'-O-(1-methylethylidene)-4'-thio-(CAS DataBase Reference)
• NIST Chemistry Reference: Adenosine, 2-chloro-N-methyl-2',3'-O-(1-methylethylidene)-4'-thio-(596103-17-2)
• EPA Substance Registry System: Adenosine, 2-chloro-N-methyl-2',3'-O-(1-methylethylidene)-4'-thio-(596103-17-2)

Safety Data

• Hazardous Substances Data: 596103-17-2(Hazardous Substances Data)

Upstream product

• 74-89-5 methylamine 
• 596103-10-5 benzoic acid (3aS,4R,6R,6aR)-6-(2,6-dichloro-purin-9-yl)-2,2-dimethyl-tetrahydro-thieno[3,4-d][1,3]dioxol-4-ylmethyl ester 

Downstream Products

• 683275-20-9 Benzoic acid (2R,3S,4R,5R)-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-5-(2-chloro-6-methylamino-purin-9-yl)-tetrahydro-thiophen-2-ylmethyl ester 
• 666750-35-2 benzoic acid (2R,3S,4R,5R)-5-[2-chloro-6-methylaminopurin-9-yl]-3,4-dihydroxy-tetrahydro-thiophen-2-ylmethyl ester 
• 596103-12-7 benzoic acid (3aS,4R,6R,6aR)-6-(2-chloro-6-methylamino-purin-9-yl)-2,2-dimethyl-tetrahydro-thieno[3,4-d][1,3]dioxol-4-ylmethyl ester 

Relevant articles and documents

N6-substituted D-4′-thioadenosine-5′-methyluronamides: Potent and selective agonists at the human A3 adenosine receptor

4′-Thio analogues 3-5 of Cl-IB-MECA (2) (Ki = 1.0 ± 0.2 nM at the human A3 adenosine receptor) were synthesized from D-gulono-γ-lactone via 4-thioribosyl acetate 14 as the key intermediate. All synthesized 4′-thionucleosides exhibite