59647-78-8

Basic information

• Product Name: 2-phenylpropionaldehyde oxime
• Synonyms: 2-phenylpropionaldehyde oxime;2-Phenyl-1-propanone oxime;Ai3-13013;Benzeneacetaldehyde, alpha-methyl-, oxime;Einecs 261-839-8
• CAS NO: 59647-78-8
• Molecular Formula: C₉H₁₁NO
• Molecular Weight: 149.18974
• EINECS: 261-839-8
• Mol File: 59647-78-8.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 270°C at 760 mmHg
• Flash Point: 157.2°C
• Appearance: /
• Density: 0.99g/cm³
• Vapor Pressure: 0.00346mmHg at 25°C
• Refractive Index: 1.514
• CAS DataBase Reference: 2-phenylpropionaldehyde oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenylpropionaldehyde oxime(59647-78-8)
• EPA Substance Registry System: 2-phenylpropionaldehyde oxime(59647-78-8)

Safety Data

• Hazardous Substances Data: 59647-78-8(Hazardous Substances Data)

Usage

General Description

2-phenylpropionaldehyde oxime is a chemical compound with the molecular formula C9H11NO. It is commonly used as a flavoring agent in the food industry, providing a sweet, floral, and slightly woody aroma. It is also used in the production of perfumes and cosmetics, as well as in pharmaceuticals. 2-phenylpropionaldehyde oxime is a colorless to pale yellow liquid with a boiling point of 287-288°C and a melting point of 40-42°C. It is not considered to be highly toxic or harmful, but appropriate safety precautions should still be taken when handling the substance.

InChI:InChI=1/C9H11NO/c1-8(7-10-11)9-5-3-2-4-6-9/h2-8,11H,1H3

Upstream product

• 34713-70-7 2-Phenylpropanal 
• 5670-65-5 1-nitro-2-phenylpropene 
• 5670-65-5 (E)-1-nitro-2-phenyl-1-propene 
• 624286-52-8 2-phenylpropyl trimethylsilyl ether 
• 874960-60-8 (2-phenylpropan-1-yloxy)tetrahydro-2H-pyran 
• 98022-57-2 1-chloro-1-methyl-2-(hydroxyimino)ethane 
• 591-51-5 phenyllithium 
• 1123-85-9 (RS)-2-phenyl-1-propanol 
• 67-56-1 methanol 
• 98-83-9 isopropenylbenzene 
• 66291-23-4 2-acetoxy-1-nitro-2-phenylpropane 
• 77-83-8 fraeseol 

Downstream Products

• 202061-61-8 2-phenylpropanohydroximoyl chloride 
• 13490-93-2 N-methyl-1-phenyl-1-methylacetamide 
• 1823-91-2 1-phenylethyl cyanide 
• 18797-91-6 (E)-N-(2-phenylprop-1-en-1-yl)acetamide 
• 126452-03-7 (S)-N-(2-phenylpropyl)acetamide 
• 492-37-5 hydratropic acid 
• 1823-91-2 (R)-α-methylbenzyl cyanide 
• 1823-91-2 (S)-α-phenylpropionitrile 
• 1424394-87-5 C₁₄H₁₇NO₃ 
• 1424394-96-6 C₁₃H₁₅NO₃ 
• 1424395-15-2 C₃₀H₂₉Cl₂N₃O₅ 
• 1318073-02-7 ethyl 5-methyl-3-(1-phenylethyl)isoxazole-4-carboxylate 
• 24277-44-9 (1-isothiocyanato-ethyl)-benzene 
• 582-22-9 2-phenylpropylamine 

Relevant articles and documents

Arylboronic Acid-Catalyzed C-Allylation of Unprotected Oximes: Total Synthesis of N-Me-Euphococcine

O-Unprotected keto-and aldoximes are readily C-allylated with allyl diisopropyl boronate in the presence of arylboronic acid catalysts to yield highly substituted N-α-secondary and tertiary homoallylic hydroxylamines. The method was used in the total synthesis of the trace alkaloid N-Me-Euphococcine.

Novel chiral phosphine ligand, metal catalyst containing chiral phosphine ligand and preparation method and application thereof

The invention provides a novel chiral phosphine ligand, a metal catalyst containing the chiral phosphine ligand and a preparation method and an application thereof. The novel chiral phosphine ligand has a structural formula shown in the attached figure; the metal catalyst is a transition metal complex which is synthesized by the novel chiral phosphine ligand and transition metal, and is used for asymmetric catalyzing and hydrogenating reaction, and catalyzing and hydrogenating to synthesize beta-arylamide with high optical purity. The novel chiral phosphine ligand has the advantages that the economic practicality is higher, the product purity is high, the carrying amount of ligand (S/C) is high, and the like.

Synthesis and evaluation of 4,5-dihydro-5-methylisoxazolin-5-carboxamide derivatives as VLA-4 antagonists

A novel set of compounds containing a 4,5-dihydro-5-methylisoxazoline have been successfully designed as VLA-4 receptor antagonists. Compound (14p) had a high receptor binding affinity of 4 nM and also found to be metabolically stable in vitro.