59755-25-8

Basic information

• Product Name: N-(3-Formylphenyl)acetamide
• Synonyms: 3-(Acetylamino)benzaldehyde;N-(3-Formylphenyl)acetamide
• CAS NO: 59755-25-8
• Molecular Formula: C₉H₉NO₂
• Molecular Weight: 163.17
• Mol File: 59755-25-8.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 370.7°C at 760 mmHg
• Flash Point: 174.5°C
• Appearance: /
• Density: 1.216g/cm³
• Vapor Pressure: 1.09E-05mmHg at 25°C
• Refractive Index: 1.622
• CAS DataBase Reference: N-(3-Formylphenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-Formylphenyl)acetamide(59755-25-8)
• EPA Substance Registry System: N-(3-Formylphenyl)acetamide(59755-25-8)

Safety Data

• Hazardous Substances Data: 59755-25-8(Hazardous Substances Data)

Usage

General Description

N-(3-Formylphenyl)acetamide, also known as 3-(N-Phenylformyl)-acetanilide, is a chemical compound with the molecular formula C10H10N2O2. It is commonly used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. This chemical is a white to off-white powder with a melting point of 175-177 degrees Celsius. It is soluble in most organic solvents and has a weak acidic property. N-(3-Formylphenyl)acetamide is known to have applications in the pharmaceutical industry, particularly in the production of anti-inflammatory and analgesic drugs. Additionally, it has been studied for its potential antioxidant and anti-cancer properties.

InChI:InChI=1/C9H9NO2/c1-7(12)10-9-4-2-3-8(5-9)6-11/h2-6H,1H3,(H,10,12)

Upstream product

• 108-24-7 acetic anhydride 
• 1709-44-0 m-aminobenzaldehyde 
• 1877-77-6 3-aminobenzenemethanol 
• 16375-94-3 N-[3-(hydroxymethyl)phenyl]acetamide 
• 96783-68-5 N-(3-(aminomethyl)phenyl)acetamide 
• 123306-28-5 N-(3-formylphenyl)acetamide 
• 619-25-0 3-Nitrobenzyl alcohol 
• 113260-07-4 N-(3-[1,3]dioxolan-2-yl-phenyl)-acetamide 
• 6398-87-4 3-aminobenzaldehyde ethylene acetal 
• 75-36-5 acetyl chloride 
• 64-17-5 ethanol 
• 141-78-6 ethyl acetate 
• 619-24-9 3-nitrobenzonitrile 
• 587-48-4 3-acetylaminobenzoic acid 

Downstream Products

• 587-48-4 3-acetylaminobenzoic acid 
• 393569-51-2 7-(3-Acetylamino-phenyl)-heptanoic acid 
• 1401067-64-8 N-(3-(hydroxy(2-nitrophenyl)methyl)phenyl)acetamide 
• 127033-96-9 N-{3-[(E)-3-Oxo-3-(3,4,5-trimethoxy-phenyl)-propenyl]-phenyl}-acetamide 
• 104155-86-4 N-(3-formyl-4-nitrophenyl)acetamide 
• 1426055-79-9 N-{3-[(Z)-2-(4-nitrophenyl)vinyl]phenyl}acetamide 
• 1338532-81-2 C₁₅H₂₃N₃O₃ 
• 1338532-84-5 2-(meta-acetamidophenyl)-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazole 3-oxide 1-oxyl 
• 1202565-98-7 N-((3-(((R)-3-(1H-indazol-5-ylamino)piperidin-1-yl)methyl)phenyl)methyl) acetamide 
• 945005-51-6 C₁₈H₁₈N₆O₂S 
• 118365-31-4 C₁₅H₁₃N₅O₅ 

Relevant articles and documents

SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES

The invention provides compounds represented by the structural formula (1): wherein R1, R2, R3, R4, R5, R6 are as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.

Validation of PqsD as an anti-biofilm target in pseudomonas aeruginosa by development of small-molecule inhibitors

2-Heptyl-4-hydroxyquinoline (HHQ) and Pseudomonas quinolone signal (PQS) are involved in the regulation of virulence factor production and biofilm formation in Pseudomonas aeruginosa. PqsD is a key enzyme in the biosynthesis of these signal molecules. Using a ligand-based approach, we have identified the first class of PqsD inhibitors. Simplification and rigidization led to fragments with high ligand efficiencies. These small molecules repress HHQ and PQS production and biofilm formation in P. aeruginosa. This validates PqsD as a target for the development of anti-infectives.

Low-pressure hydrogenation of arenecarboxylic acids to aryl aldehydes

A highly effective palladium catalyst has been developed that allows the selective hydrogenation of arenecarboxylic acids to the aryl aldehydes in the presence of pivalic anhydride already at 5 bar hydrogen pressure. With the new catalyst, diversely functionalized aromatic and heteroaromatic aldehydes are conveniently accessible from the corresponding carboxylic acids in a single reaction step without any overreduction to the alcohols.