5980-23-4Relevant articles and documents
Visible light-mediated synthesis of amides from carboxylic acids and amine-boranes
Chen, Xuenian,Kang, Jia-Xin,Ma, Yan-Na,Miao, Yu-Qi
supporting information, p. 3595 - 3599 (2021/06/06)
Here, a photocatalytic deoxygenative amidation protocol using readily available amine-boranes and carboxylic acids is described. This approach features mild conditions, moderate-to-good yields, easy scale-up, and up to 62 examples of functionalized amides with diverse substituents. The synthetic robustness of this method was also demonstrated by its application in the late-stage functionalization of several pharmaceutical molecules.
Base-Mediated Amination of Alcohols Using Amidines
Chen, Jianbin,Fang, Yanchen,Jia, Xiaofei,Jiang, Shaohua,Li, Zehua,Liang, Zuyu,Lu, Fenghong,Qi, Shuo,Ren, Chaoyu,Yu, Shuangming,Zhang, Chunyan,Zhang, Guoying,Zhang, Sheng
, p. 7728 - 7738 (2020/07/15)
Novel and efficient base-mediated N-alkylation and amidation of amidines with alcohols have been developed, which can be carried out in one-pot reaction conditions, which allows for the synthesis of a wide range of N-alkyl amines and free amides in good to excellent yields with high atom economy. In contrast to borrowing hydrogen/hydrogen autotransfer or oxidative-type N-alkylation reactions, in which alcohols are activated by transition-metal-catalyzed or oxidative aerobic dehydrogenation, the use of amidines provides an effective surrogate of amines. This circumvents the inherent necessity in N-alkylation of an oxidant or a catalyst to be stabilized by ligands.
Tetrazole urease inhibitor type feed additive and preparation method thereof
-
Paragraph 0018; 0024; 0025; 0026; 0027; 0028; 0029, (2019/02/04)
The invention discloses a tetrazole urease inhibitor type feed additive and a preparation method thereof and belongs to the technical field of synthesis of feed additives. According to the technical scheme, a structural formula of the tetrazole urease inhibitor type feed additive is shown in the description. The invention further discloses the preparation method of the tetrazole urease inhibitor type feed additive. The tetrazole urease inhibitor type feed additive prepared by the preparation method can be used as non-protein nitrogen and has a certain inhibition effect on urease; the tetrazoleurease inhibitor type feed additive has the effects of sterilizing and resisting ulcer and has a potential of being used as an excellent animal feed additive.