59908-70-2

Basic information

• Product Name: 4-(1,2,4-oxadiazol-3-yl)Benzenamine
• Synonyms: 4-(1,2,4-oxadiazol-3-yl)Benzenamine;4-(1,2,4-OXADIAZOL-3-YL)ANILINE(WXG02413)
• CAS NO: 59908-70-2
• Molecular Formula: C₈H₇N₃O
• Molecular Weight: 161.16068
• Mol File: 59908-70-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 336.1±44.0 °C(Predicted)
• Appearance: /
• Density: 1.276±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 1.98±0.10(Predicted)
• CAS DataBase Reference: 4-(1,2,4-oxadiazol-3-yl)Benzenamine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1,2,4-oxadiazol-3-yl)Benzenamine(59908-70-2)
• EPA Substance Registry System: 4-(1,2,4-oxadiazol-3-yl)Benzenamine(59908-70-2)

Safety Data

• Hazardous Substances Data: 59908-70-2(Hazardous Substances Data)

Usage

General Description

4-(1,2,4-oxadiazol-3-yl)Benzenamine, also known as benzeneamine, is a chemical compound with the molecular formula C7H6N4O. It is a derivative of aniline with an oxadiazole ring substituted at the para position of the benzene ring. 4-(1,2,4-oxadiazol-3-yl)Benzenamine has been studied for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals and agrochemicals. It exhibits a range of biological activities, making it of interest for researchers in the fields of pharmacology and chemical biology. Furthermore, 4-(1,2,4-oxadiazol-3-yl)Benzenamine is a valuable building block for the synthesis of various heterocyclic compounds and can be used as a precursor in organic synthesis. However, its potential hazards and toxicity should be considered when handling this chemical.

Upstream product

• 619-72-7 4-nitrobenzonitrile 
• 16013-14-2 3-(4-nitrophenyl)-[1,2,4]oxadiazole 
• 1613-86-1 N-hydroxy-4-nitrobenzamidine 

Downstream Products

• 96898-49-6 (4-[1,2,4]Oxadiazol-3-yl-phenyl)-[1-(1H-pyrrol-2-yl)-meth-(E)-ylidene]-amine 
• 96898-48-5 [1-(5-Nitro-furan-2-yl)-meth-(E)-ylidene]-(4-[1,2,4]oxadiazol-3-yl-phenyl)-amine 
• 96898-47-4 [1-(4-Chloro-3-nitro-phenyl)-meth-(E)-ylidene]-(4-[1,2,4]oxadiazol-3-yl-phenyl)-amine 
• 59908-73-5 (4-[1,2,4]oxadiazol-3-yl-phenyl)-carbamic acid 2,2,2-trichloro-ethyl ester 
• 841301-32-4 N-(2-((4-(1,2,4-oxadiazol-3-yl)phenyl)amino)-2-oxoethyl)-N-(2,6-dimethylphenyl)tetrahydro-2H-thiopyran-4-carboxamide 1,1-dioxide 
• 1187889-81-1 3-[4-(2-bromo-benzoyl)-piperazin-1-yl]-N-(4-[1,2,4]oxadiazol-3-yl-phenyl)-3-oxo-propionamide 
• 1187889-78-6 N-(4-[1,2,4]oxadiazol-3-yl-phenyl)-3-oxo-3-[4-(3,4,5-trifluoro-benzoyl)-piperazin-1-yl]-propionamide 
• 1187889-68-4 N-(4-[1, 2, 4]oxadiazol-3-yl-phenyl)-3-oxo-3-[4-(2-trifluoromethyl-benzoyl)-piperazin-1-yl]-propionamide 
• 54608-86-5 5-(4-isothicyanatophenyl)-1,2,4-oxadiazole 
• 59908-71-3 <4-(1,2,4-oxadiazol-3-yl)phenyl>carbamic acid methyl ester 
• 96898-46-3 3-<4-<<(4-chlorophenyl)methylene>amino>phenyl>-1,2,4-oxadiazole 
• 59908-72-4 [4-(1,2,4-Oxadiazol-3-yl)phenyl]carbamic acid, phenyl ester 
• 1188372-71-5 3-[4-(2-chloro-phenoxy)-piperidin-1-yl]-N-(4-[1,2,4]oxadiazol-3-yl-phenyl)-3-oxo-propionamide 

Relevant articles and documents

NEW PROCESS FOR THE PREPARATION OF AMENAMEVIR

The present invention relates to an improved process for the preparation of Amenamevir and derivatives thereof via a four component Ugi reaction.

THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHOD OF USE

Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1 comprising administering to a subject in need thereof a compound described here.

NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE

The present invention relates to piperidine derivatives that act as inhibitors of stearoyl-CoA desaturase. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.