1613-86-1

Basic information

• Product Name: N-HYDROXY-4-NITRO-BENZAMIDINE
• Synonyms: 4-NitrobenzaMidoxiMe, 97%;N-Hydroxy-4-nitrobenziMidaMide;Benzenecarboximidamide, N-hydroxy-4-nitro-;N'-Hydroxy-4-nitrobenzenecarboximidamide
• CAS NO: 1613-86-1
• Molecular Formula: C₇H₇N₃O₃
• Molecular Weight: 181.15
• Mol File: 1613-86-1.mol
• Article Data: 8

Chemical Properties

• Melting Point: 180 °C
• Boiling Point: 410.8°Cat760mmHg
• Flash Point: 202.3°C
• Appearance: /
• Density: 1.49g/cm³
• Vapor Pressure: 1.74E-07mmHg at 25°C
• Refractive Index: 1.643
• Storage Temp.: 2-8°C
• PKA: 13.11±0.50(Predicted)
• CAS DataBase Reference: N-HYDROXY-4-NITRO-BENZAMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-HYDROXY-4-NITRO-BENZAMIDINE(1613-86-1)
• EPA Substance Registry System: N-HYDROXY-4-NITRO-BENZAMIDINE(1613-86-1)

Safety Data

• Hazardous Substances Data: 1613-86-1(Hazardous Substances Data)

Usage

General Description

N-HYDROXY-4-NITRO-BENZAMIDINE, also known as N-[(4-nitrophenyl)carbamimidoyl]hydroxylamine, is a chemical compound with the molecular formula C7H7N3O3. It is a synthetic organic compound that is widely used in the pharmaceutical industry as a building block for the synthesis of various drugs and other bioactive molecules. This chemical is known for its nitro group, which can undergo reduction reactions to form amino compounds, making it a valuable precursor in organic synthesis. N-HYDROXY-4-NITRO-BENZAMIDINE has applications in drug discovery and development, as well as in academic research for the synthesis of novel compounds with potential pharmaceutical properties. Additionally, it is used as a reagent in organic chemistry processes to introduce specific functional groups into organic molecules. Overall, this compound plays a significant role in the development of pharmaceutical and chemical products.

InChI:InChI=1/C7H7N3O3/c8-7(9-11)5-1-3-6(4-2-5)10(12)13/h1-4,11H,(H2,8,9)

Upstream product

• 619-72-7 4-nitrobenzonitrile 
• 5470-11-1 hydroxylamine hydrochloride 
• 584-08-7 potassium carbonate 

Downstream Products

• 54608-85-4 3-(4-nitrophenyl)-5-(3,4,5-trimethoxyphenyl)-1,2,4-oxadiazole 
• 952-89-6 (E)-N'-acetoxy-4-nitrobenzimidamide 
• 25283-96-9 3-(4-methoxyphenyl)-5-methyl-1,2,4-oxadiazole 
• 224963-67-1 N-(methoxycarbonyl)oxy-4-nitrobenzamidine 
• 841301-32-4 N-(2-((4-(1,2,4-oxadiazol-3-yl)phenyl)amino)-2-oxoethyl)-N-(2,6-dimethylphenyl)tetrahydro-2H-thiopyran-4-carboxamide 1,1-dioxide 
• 54608-98-9 5-(pyridin-2-yl)-3-(4-nitrophenyl)-1,2,4-oxadiazole 
• 25283-95-8 3-(4-nitro)phenyl-5-phenyl-[1,2,4]oxadiazole 
• 16013-14-2 3-(4-nitrophenyl)-[1,2,4]oxadiazole 
• 73217-52-4 N,N-dimethyl-N'-[3-(4-nitro-phenyl)-[1,2,4]oxadiazol-5-ylmethylene]-benzene-1,4-diamine N'-oxide 
• 73217-41-1 1-[3-(4-nitro-phenyl)-[1,2,4]oxadiazol-5-ylmethyl]-pyridinium; chloride 
• 59908-71-3 <4-(1,2,4-oxadiazol-3-yl)phenyl>carbamic acid methyl ester 
• 59908-70-2 4-[1,2,4]oxadiazol-3-yl-phenylamine 
• 96898-47-4 [1-(4-Chloro-3-nitro-phenyl)-meth-(E)-ylidene]-(4-[1,2,4]oxadiazol-3-yl-phenyl)-amine 
• 96898-48-5 [1-(5-Nitro-furan-2-yl)-meth-(E)-ylidene]-(4-[1,2,4]oxadiazol-3-yl-phenyl)-amine 

Relevant articles and documents

NEW PROCESS FOR THE PREPARATION OF AMENAMEVIR

The present invention relates to an improved process for the preparation of Amenamevir and derivatives thereof via a four component Ugi reaction.

NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE

The present invention relates to piperazine derivatives that act as inhibitors of stearoyl-CoA desaturase. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.

HYDRAZONE DERIVATIVE

A compound represented by the following formula (I): wherein R1 represents hydrogen, aryl which may have a substituent, a saturated or unsaturated 5- to 7-membered heterocyclic group which may have a substituent, etc.; R2 represents hydrogen, aryl which may have a substituent, a saturated or unsaturated 5- to 7-membered heterocyclic group which may have a substituent, etc.; R3 represents hydrogen, etc.; Ar represents a divalent group derived from aromatic hydrocarbon, etc.; X represents a single bond, linear or branched alkylene having from 1 to 3 carbon atoms which may have a substituent, etc.; and G represents halogen, a saturated or unsaturated 5- or 6-membered cyclic hydrocarbon group which may have a substituent, a saturated or unsaturated 5- to 7-membered heterocyclic group which may have a substituent, etc., a salt thereof or a solvate thereof; and an agent for inhibiting aggregation and/or deposition of an amyloid protein or an amyloid-like protein, which comprises the compound, a salt thereof or a solvate thereof