59944-76-2 Usage
Uses
Used in Pharmaceutical Research:
THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID is used as a key reagent in the study of neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives. Its unique structure allows it to be a promising candidate for the development of therapeutic agents targeting Alzheimer's disease.
Used in Alzheimer's Disease Treatment:
In the context of Alzheimer's disease, THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID is utilized as a component in the design and synthesis of novel compounds with potential neuroprotective effects. These compounds aim to mitigate the cognitive decline and neuronal degeneration associated with the disease by modulating the cholinergic system, which plays a crucial role in memory and cognitive function.
Used in Medicinal Chemistry:
THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID serves as a valuable building block in the synthesis of various bioactive molecules. Its presence in a molecule can influence its pharmacokinetic and pharmacodynamic properties, making it an important component in the development of new drugs with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 59944-76-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,9,4 and 4 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 59944-76:
(7*5)+(6*9)+(5*9)+(4*4)+(3*4)+(2*7)+(1*6)=182
182 % 10 = 2
So 59944-76-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H5NO2S/c10-8(11)6-4-5-2-1-3-9-7(5)12-6/h1-4H,(H,10,11)
59944-76-2Relevant academic research and scientific papers
SULFONAMIDES AS TRPM8 MODULATORS
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, (2012/07/31)
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows: wherein A, B, G, Y, R1, R2, R3, and R4 are defined herein.
Azabicyclic-substituted fused-heteroaryl compounds for the treatment of disease
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, (2008/06/13)
The invention provides compounds of Formula I: wherein Azabicyclo is These compounds may be in the form of pharmaceutical salts or compositions, racemic mixtures, or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals in which α7 is known to be involved.
Quinuclidines-substituted-multi-cyclic-heteroaryls for the treatment of disease
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, (2008/06/13)
The invention provides compounds of Formula I: 1where in W is 2These compounds may be in the form of pharmaceutical salts or compositions, racemic mixtures, or pure enantiomers thereof. The compounds of Formula I are useful to treat diseases or conditions in which α7 is known to be involved.
