6002-99-9

Upstream product

• 5279-16-3 DL-4-Nitro-4-phenyl-hexansaeure-methylester 
• 135815-65-5 methyl 4-phenylhex-3-enoate 
• 14273-89-3 methyl 6-chlorohexanoate 
• 71-43-2 benzene 
• 13894-61-6 methyl (E)-hex-3-enoate 
• 25333-24-8 3-benzoylpropionic acid methyl ester 
• 134953-19-8 (E)-4-phenylhex-3-enoic acid 
• 67545-37-3 4-hydroxy-4-phenyl-hexanoic acid 
• 5279-14-1 1-phenyl-1-nitropropane 
• 2114-36-5 1-bromopropylbenzene 

Downstream Products

• 74072-53-0 methyl 4-(4-acetylphenyl)hexanoate 

Relevant academic research and scientific papers

Friedel-Crafts alkylation of benzene and toluene with olefinic C6 hydrocarbons and esters

To assist our study of the reaction of toluene and other aromatic compounds with methyl oleate and other olefinic esters, benzene and toluene have been alkylated under Friedel-Crafts conditions with hex-1-ene, hex-3-ene, methyl hex-3-enoate and methyl hex-3-enedioate. The products were isolated and identified by NMR and mass spectrometric procedures.

A New Approach to Aromatic Substitution - para-Specific Alkylation of Acetophenone by Alkyl Radicals in Strongly Acidic Media

Acetophenone in 25percent oleum is substituted by various alkyl radicals specifically in the para-position.The radicals used include cyclohexyl, 3-chloro-1-methylpropyl, 3-bromo-1-methylpropyl, 4-chloro-1-methylbutyl, 4-bromo-1-methylbutyl, 5-bromo-1-methylpentyl, 5-acetoxy-1-methylpentyl, 3-carboxy-1-methylpropyl, 4-carboxy-1-methylbutyl and 5-carboxy-1-methylpentyl.They were all generated by hydrogen atom abstraction at the radical position by dimethylaminium radicals, generated in turn from protonated dimethylchloramine and ferrous sulphate.Yields were generally poor to moderate but utilised simple conditions and cheap reagents.