6003-05-0

Basic information

• Product Name: L-Alanine hydrochloride
• Synonyms: L-ALANINE HYDROCHLORIDE SOLUTION;L-Alanine hydrochloride;L-Alanine solution hydrochloride;Ala-OH·Hydrochloride;(S)-2-aMinopropanoic acid hydrochloride;L-Alanine,hydrochloride (1:1)
• CAS NO: 6003-05-0
• Molecular Formula: C₃H₇NO₂*ClH
• Molecular Weight: 125.55
• EINECS: 227-849-1
• Product Categories: AA to ALLife Sciences Standards;A;Alphabetic;Amino Acids;Amino Acids, Peptides and Proteins
• Mol File: 6003-05-0.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 212.9 °C at 760 mmHg
• Flash Point: 82.6 °C
• Appearance: /
• Density: 1.546g/cm³
• Vapor Pressure: 2.17E-05mmHg at 25°C
• Refractive Index: 1.576
• Storage Temp.: 2-8°C
• BRN: 4296703
• CAS DataBase Reference: L-Alanine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: L-Alanine hydrochloride(6003-05-0)
• EPA Substance Registry System: L-Alanine hydrochloride(6003-05-0)

Safety Data

• WGK Germany: 2
• F: 10
• Hazardous Substances Data: 6003-05-0(Hazardous Substances Data)

Usage

General Description

L-Alanine hydrochloride is a chemical compound that consists of the amino acid L-alanine combined with hydrochloric acid. It is a white crystalline powder that is highly soluble in water. L-Alanine is one of the 20 amino acids that are essential for protein synthesis in the human body. L-Alanine hydrochloride is commonly used in biochemical research and as a component in the production of pharmaceuticals, food additives, and other chemicals. It is also used in the development of parenteral and enteral nutrition formulations due to its role in promoting muscle protein synthesis and maintaining a healthy nitrogen balance in the body. L-Alanine hydrochloride is considered to be safe for consumption when used in accordance with regulatory guidelines.

InChI:InChI=1/C15H11BrF3NO2/c1-22-13-6-5-10(16)8-12(13)14(21)20-11-4-2-3-9(7-11)15(17,18)19/h2-8H,1H3,(H,20,21)

Upstream product

• 15761-38-3 L-N-Boc-Ala 
• 15180-22-0 (3S,6S)-3-methyl-6-(phenylmethyl)piperazine-2,5-dione 
• 1803-60-7 (3S,6S)-3-methyl-6-(2-methylpropyl)piperazine-2,5-dione 
• 56-41-7 L-alanin 
• 1334715-65-9 versicoloritide A 
• 1186048-83-8 desmocyclopeptide 
• 117049-08-8 (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl<(tert-butoxycarbonyl)amino>bromoacetate 
• 226387-97-9 (αS,3R)-4,4-dimethyl-2-oxo-1-phenylpyrrolidin-3-yl α-phthalimidopropanoate 
• 13515-97-4 methyl 2-aminopropanoate monohydrochloride 
• 110449-46-2 <(1S,2R)-10-(N,N-dicyclohexylaminosulfonyl)born-2-yl> (2R)-2-aminopropionate 
• 131968-99-5 (1'S,5S)-1-(benzyloxycarbonyl)-3-(1'-phenyleth-1'-yl)-5-methylimidazolidin-4-one 
• 7585-47-9 N-benzyl-(S)-alanine 
• 3082-75-5 L-Alanine ethyl ester 

Downstream Products

• 39825-33-7 isopropyl L-alanine 
• 35661-39-3 N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine 
• 2749-11-3 (S)-Alaninol 
• 15136-29-5 (S)-methyl 2-((S)-2-((tert-butoxycarbonyl)amino)-3-phenylpropanamido)propanoate 
• 16480-55-0 sodium L-alaninate 
• 847406-01-3 2-{[4'-(2,3-dichlorophenyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-carbonyl]amino}propionic acid methyl ester 
• 2224-52-4 L-alanine N-carboxyanhydride 
• 2491-20-5 L-alanine methyl ester hydrochloride 
• 24960-20-1 Cbz-glycyl-leucyl-alanine 
• 407-23-8 N-(trifluoroacetyl)-L-alanine 
• 18409-49-9 N-carbamoyl-L-alanine 

Relevant articles and documents

Solvent-freeN-Boc deprotection byex situgeneration of hydrogen chloride gas

An efficient, scalable and sustainable method for the quantitative deprotection of thetert-butyl carbamate (N-Boc) protecting group is described, using down to near-stoichiometric amounts of hydrogen chloride gas in solvent-free conditions. We demonstrate theex situgeneration of hydrogen chloride gas from sodium chloride and sulfuric acid in a two-chamber reactor, introducing a straightforward method for controlled and stoichiometric release of HCl gas. The solvent-free conditions allow deprotection of a wide variety ofN-Boc derivatives to obtain the hydrochloride salts in quantitative yields. The procedure obviates the need for any work-up or purification steps providing an uncomplicated green alternative to standard methods. Due to the solvent-free, anhydrous conditions, this method shows high tolerance towards acid sensitive functional groups and furnishes expanded functional group orthogonality.

L-Tryptophan l-tryptophanium chloride

l-Tryptophan l-tryptophanium chloride is a new salt with (A?A+) type dimeric cation. It crystallizes in the monoclinic system (space group P21, Z = 2). The asymmetric unit contains one zwitterionic l-tryptophan molecule, one l-tryptophanium cation and one chloride anion. The dimeric cation is formed by a OH?O hydrogen bond with the O?O distance equal to 2.5556(18) ?. The infrared and Raman spectra of the crystal are studied and compared with the spectra of l-tryptophanium chloride.

Cyclopeptides and polyketides from coral-associated fungus, Aspergillus versicolor LCJ-5-4

Three new cyclopentapeptides, versicoloritides A-C (1-3), a new orcinol tetramer, tetraorcinol A (4), and two new lactones, versicolactones A and B (5 and 6) together with three known metabolites, diorcinol, glyantrypine, and cordyol C were isolated from the fermentation broth of the coral-associated fungus Aspergillus versicolor LCJ-5-4. Their structures were elucidated by spectroscopic and chemical methods. The new compounds 1-4 were evaluated for their radical-scavenging activity and antimicrobial activity against Staphylococcus aureus, Escherichia coli, Enterobacter aerogenes, Bacillus subtilis, Pseudomonas aeruginosa, and Candida albicans and cytotoxicity against P388 and Hela cell lines. Compound 4 showed weak radical-scavenging activity against the DPPH radical with an IC50 value of 67 μM.