39825-33-7

Basic information

• Product Name: L-Alanine Isopropyl Ester Hydrochloride
• Synonyms: H-ALA-OIPR HCL;H-Ala-OiPro.HCl;L-Alanine isopropyl ester hydrochloride;L-Alanine, 1-methylethyl ester (9CI);H-ALA-OIPHCL;2-Aminopropionic acid isopropyl ester hydrochloride;(S)-isopropyl 2-aminopropanoate hydrochloride;L-Alanine, 1-Methylethyl ester
• CAS NO: 39825-33-7
• Molecular Formula: C₆H₁₃NO₂
• Molecular Weight: 167.63
• Product Categories: GLYCINESCAFFOLD;Amino Acids Derivatives;Alanine [Ala, A];Amino Acids and Derivatives
• Mol File: 39825-33-7.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 145.7 °C at 760 mmHg
• Flash Point: 20.7 °C
• Appearance: /
• Density: 0.968±0.06 g/cm3(Predicted)
• Storage Temp.: Store at 0-5°C
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 8.11±0.29(Predicted)
• Stability: Very Hygroscopic
• CAS DataBase Reference: L-Alanine Isopropyl Ester Hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: L-Alanine Isopropyl Ester Hydrochloride(39825-33-7)
• EPA Substance Registry System: L-Alanine Isopropyl Ester Hydrochloride(39825-33-7)

Safety Data

• Hazardous Substances Data: 39825-33-7(Hazardous Substances Data)

Usage

Uses

(S)-Isopropyl-2-aminopropanoate Hydrochloride, is a chemical reagent used in the synthesis of anti-HCV prodrugs based on imidazotriazine and pyrrolotriazine molecules.

Upstream product

• 6003-05-0 L-alanine hydrochloride 
• 67-63-0 isopropyl alcohol 
• 10065-72-2 L-Alanine methyl ester 
• 56-41-7 L-alanin 
• 302-72-7 rac-Ala-OH 
• 39613-92-8 alanine isopropyl ester hydrochloride 

Downstream Products

• 56-41-7 L-alanin 
• 338-69-2 D-Alanine 
• 67-63-0 isopropyl alcohol 
• 2053424-88-5 (2S)-isopropyl2-((((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoate 
• 379270-37-8 (S)-isopropyl-2-(((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoate 
• 1604813-64-0 C₂₅H₃₂ClFN₆O₁₀P₂ 
• 1256490-49-9 (S)-2-[(R)-(4-nitro-phenoxy)-phenoxy-phosphorylamino]propionic acid isopropyl ester 
• 1256490-31-9 (S)-2-[(S)-(4-nitro-phenoxy)-phenoxy-phosphorylamino]propionic acid isopropyl ester 
• 1883563-86-7 9-[(R)-2-[[bis[[-(S)-1-(isopropoxycarbonyl)ethyl]amino]phosphinyl]methoxy]propyl]adenine 
• 383365-04-6 N-[(R)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphonyl]-L-alanine-1-methylethyl ester 
• 1392275-56-7 9-[(R)-2-[[(R)-1-[[(S)-(isopropoxycarbonyl)ethyl]amino]phenoxyphosphinyl]methoxy]propyl]adenine monofumarate 
• 126402-81-1 isopropyl 2-[(E)-1-phenylmethylideneamino]propanoate 
• 245338-81-2 isopropyl 2-[(E)-1-(4-chlorophenyl)methylideneamino]propanoate 
• 245338-82-3 N-4-fluorobenzylidene-DL-Ala isopropyl ester 

Relevant articles and documents

A Method for the Determination of the pKa of the α-Hydrogen in Amino Acids Using Racemization and Exchange Studies

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Antiviral novel nucleoside reverse transcriptase inhibitors

The invention relates to compounds of antiviral novel nucleoside reverse transcriptase inhibitors, pharmaceutical compositions containing the compounds, and preparation and use of the compounds, and particularly discloses fused pyrimidine compounds shown in formula (I) and the pharmaceutical compositions containing the compounds, pharmaceutically acceptable salts, stereoisomers, solvates, hydrates, crystal forms, prodrugs or isotope derivatives. The compounds can be used for treating and/or preventing viral infectious diseases, such as human immunodeficiency virus (HIV) and hepatitis B virus (HBV). The formula (I) is shown in the specification.

Puerarin derivative and preparation method and application thereof

The invention relates to a puerarin derivative and a preparation method and an application thereof. The puerarin derivative is prepared through six steps of reactions by taking puerarin and L-alanineisopropyl ester hydrochloride as main raw materials. The puerarin derivative not only has good water solubility, but also has good anti-platelet aggregation action and can be used for preparing anti-platelet aggregation drugs. In addition, the reaction conditions of the reactions for preparing the puerarin derivative are mild, and the synthetic method is simple.