60186-20-1 Usage
Uses
Used in Organic Synthesis:
2,6-difluoro-3-nitropyridin-4-aMine is utilized as a building block in organic synthesis for the creation of various functionalized molecules. Its unique structure and functional groups make it a valuable component in the development of new compounds with specific properties.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,6-difluoro-3-nitropyridin-4-aMine is used as a key intermediate in the synthesis of potential drug candidates. Its presence in these molecules can enhance their pharmacological properties, such as bioavailability, potency, and selectivity, making it a valuable asset in drug discovery and development.
Used in Agrochemicals:
2,6-difluoro-3-nitropyridin-4-aMine also finds application in the agrochemical sector, where it is used as a precursor in the synthesis of novel pesticides and herbicides. The incorporation of 2,6-difluoro-3-nitropyridin-4-aMine into agrochemical products can lead to the development of more effective and environmentally friendly solutions for pest and weed control.
Used in Materials Science:
In the field of materials science, 2,6-difluoro-3-nitropyridin-4-aMine is employed in the development of advanced materials with specific characteristics. Its unique structure and functional groups can contribute to the creation of materials with improved properties, such as enhanced stability, reactivity, or selectivity, for various applications.
It is crucial to handle 2,6-difluoro-3-nitropyridin-4-aMine with care, as it is a potentially hazardous material. Proper safety precautions should be taken when working with 2,6-difluoro-3-nitropyridin-4-aMine to ensure the safety of individuals and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 60186-20-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,1,8 and 6 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 60186-20:
(7*6)+(6*0)+(5*1)+(4*8)+(3*6)+(2*2)+(1*0)=101
101 % 10 = 1
So 60186-20-1 is a valid CAS Registry Number.
60186-20-1Relevant academic research and scientific papers
Novel nucleosides and related processes, pharmaceutical compositions and methods
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Page/Page column 13; Figure 2, (2010/02/07)
The invention provides novel nucleosides and related processes, pharmaceutical compositions, and methods. The novel nucleosides are useful in a wide variety of antiviral, antineoplastic, and antibacterial applications. Preferred embodiments of the instant invention include novel 2 halogen-substituted, 3 halogen-substituted, and 2′,3′dihalogen-substituted analogues of 3-deazaadenosine, and novel 3 halogen-substituted analogues of 3-deazaguanosine. Compounds of the instant invention, including 4-Amino-6-fluoro-1-(β-D-ribofuranosyl)imidazo[4,5-c]pyridine and 6-Amino-7-bromo-1,5-dihydro-1-β-D-ribofuranosylimidazo[4,5-c]pyridin-4-one, have exhibited potent antiviral and anticancer activity in vitro. The compounds are also useful in the concomitant treatment of bacterial infections associated with viral infections such as AIDS.
Synthesis of halogen-substituted 3-deazaadenosine and 3-deazaguanosine analogues as potential antitumor/antiviral agents
Liu,Luo,Mozdziesz,Lin,Dutschman,Gullen,Cheng,Sartorelli
, p. 1975 - 2000 (2007/10/03)
Various 2-halogen-substituted analogues (38, 39, 43 and 44), 3-halogensubstituted analogues (51 and 52), and 2′,3′ -dihalogen- substituted analogues (57-60) of 3-deazaadenosine and 3-halogen-substituted analogues (61 and 62) of 3-deazaguanosine have been synthesized as potential anticancer and/or antiviral agents. Among these compounds, 3-deaza-3-bromoguanosine (62) showed significant cytotoxicity against L1210, P388, CCRF-CEM and B16F10 cell lines in vitro, producing IC50 values of 3, 7, 9 and 7μM, respectively. Several 3-deazaadenosine analogues (38, 51, 57 and 59) showed moderate to weak activity against hepatitis B virus.
