602-37-9

Usage

Uses

Used in Pharmaceutical Industry:
1-chloro-8-nitronaphthalene is used as a precursor in the synthesis of various organic compounds and pharmaceuticals, playing a crucial role in the development of new medications.
Used in Dye and Pigment Manufacturing:
1-chloro-8-nitronaphthalene is utilized in the production of dyes, pigments, and optical brighteners, contributing to the coloration and enhancement of various products.
Safety Considerations:
Due to its moderately toxic nature, 1-chloro-8-nitronaphthalene may cause irritation to the skin, eyes, and respiratory system upon exposure. Therefore, it should be handled and stored with caution to prevent any potential hazards.

InChI:InChI=1/C10H6ClNO2/c11-8-5-1-3-7-4-2-6-9(10(7)8)12(13)14/h1-6H

Upstream product

• 86-57-7 1-Nitronaphthalene 
• 3229-89-8 8-nitro-1-naphthylamine 
• 7697-37-2 nitric acid 
• 90-13-1 1-Chloronaphthalene 
• 7782-50-5 chlorine 
• 7705-08-0 iron(III) chloride 
• 7647-01-0 hydrogenchloride 
• 117-41-9 1-nitronaphthalene-8-sulphonic acid 
• 14380-61-1 hypochlorite 
• 95-50-1 1,2-dichloro-benzene 
• 87-61-6 1,2,3-trichlorobenzene 

Downstream Products

• 65253-31-8 8-chloro-1-naphthol 
• 63921-08-4 1-chloro-4,8-dinitronaphthalene 
• 59107-51-6 8-chloronaphthalen-1-amine 
• 128923-96-6 8-(benzyloxy)-1-chlornaphthalin 

Relevant academic research and scientific papers

PROCESS FOR SYNTHESIS OF AROMATIC COMPOUNDS

The present invention refers to a process for preparing a compound of the formula (I) wherein R denotes an organic radical which, together with the two carbon atoms to which it is bonded, forms a carbocyclic or heterocyclic ring; R1, R2, R3 and X, independently, denote hydrogen, halogen, nitro, cyano or an organic radical; or R1 and R2 or R2 and R3, together with the carbon atoms to which they are bonded, form a ring; which comprises exposing a compound of the formula (II) wherein R1, R2, R3 and X are defined as given above and Y and Z, independently, have one of the meanings of X; to an energy source in the presence of a catalyst system.

A remarkably simple and efficient benzannulation reaction

(Chemical Equation Presented) On a short fuse: Although fused aromatic rings are common structural motifs in natural products, there are relatively few direct methods for the preparation of such systems from acyclic precursors. An atom-transfer radical cyclization carried out under microwave (MW) irradiation has now been developed which gives rapid access to functionalized aromatic compounds from readily available starting materials (see scheme).