602-37-9

Usage

Uses

Used in Pharmaceutical Industry:
1-chloro-8-nitronaphthalene is used as a precursor in the synthesis of various organic compounds and pharmaceuticals, playing a crucial role in the development of new medications.
Used in Dye and Pigment Manufacturing:
1-chloro-8-nitronaphthalene is utilized in the production of dyes, pigments, and optical brighteners, contributing to the coloration and enhancement of various products.
Safety Considerations:
Due to its moderately toxic nature, 1-chloro-8-nitronaphthalene may cause irritation to the skin, eyes, and respiratory system upon exposure. Therefore, it should be handled and stored with caution to prevent any potential hazards.

InChI:InChI=1/C10H6ClNO2/c11-8-5-1-3-7-4-2-6-9(10(7)8)12(13)14/h1-6H

Upstream product

• 86-57-7 1-Nitronaphthalene 
• 3229-89-8 8-nitro-1-naphthylamine 
• 90-13-1 1-Chloronaphthalene 
• 7697-37-2 nitric acid 
• 7782-50-5 chlorine 
• 7705-08-0 iron(III) chloride 
• 7647-01-0 hydrogenchloride 
• 117-41-9 1-nitronaphthalene-8-sulphonic acid 
• 14380-61-1 hypochlorite 
• 95-50-1 1,2-dichloro-benzene 
• 87-61-6 1,2,3-trichlorobenzene 

Downstream Products

• 65253-31-8 8-chloro-1-naphthol 
• 63921-08-4 1-chloro-4,8-dinitronaphthalene 
• 59107-51-6 8-chloronaphthalen-1-amine 
• 128923-96-6 8-(benzyloxy)-1-chlornaphthalin 

Relevant academic research and scientific papers

A remarkably simple and efficient benzannulation reaction

(Chemical Equation Presented) On a short fuse: Although fused aromatic rings are common structural motifs in natural products, there are relatively few direct methods for the preparation of such systems from acyclic precursors. An atom-transfer radical cyclization carried out under microwave (MW) irradiation has now been developed which gives rapid access to functionalized aromatic compounds from readily available starting materials (see scheme).

PROCESS FOR SYNTHESIS OF AROMATIC COMPOUNDS

The present invention refers to a process for preparing a compound of the formula (I) wherein R denotes an organic radical which, together with the two carbon atoms to which it is bonded, forms a carbocyclic or heterocyclic ring; R1, R2, R3 and X, independently, denote hydrogen, halogen, nitro, cyano or an organic radical; or R1 and R2 or R2 and R3, together with the carbon atoms to which they are bonded, form a ring; which comprises exposing a compound of the formula (II) wherein R1, R2, R3 and X are defined as given above and Y and Z, independently, have one of the meanings of X; to an energy source in the presence of a catalyst system.