602281-32-3Relevant academic research and scientific papers
Simple and effective method for the deracemization of ethyl 1-hydroxyphosphinate using biocatalysts with lipolytic activity
Majewska, Paulina,Kafarski, Pawel,Lejczak, Barbara
, p. 2870 - 2875 (2006)
The kinetic resolution of ethyl (1-hydroxyethyl)phenylphosphinate was carried by enzymatic esterification with vinyl butyrate or by hydrolysis of ethyl (1-butyryloxyethyl)phenylphosphinate either by the use of lipases or whole cells of microorganisms (bac
Synthesis of bifunctional P-chiral hydroxy phosphinates; Lipase-catalyzed stereoselective acylation of ethyl (1-hydroxyalkyl)phenylphosphinates
Shioji, Kosei,Tashiro, Aya,Shibata, Sanae,Okuma, Kentaro
, p. 1103 - 1105 (2003)
Lipase-catalyzed acylation of ethyl (1-hydroxyalkyl)phenylphosphinates afforded a single diastereomer in high enantiomeric excess. The substituent effect of the alkyl group toward the acylation using Candida antractica (CAL) was larger than that of an imm
Enzymatic resolution of ethyl α-hydroxyphosphinates in a modified reaction environment
Majewska, Paulina,Lejczak, Barbara,Kafarski, Pawel
experimental part, p. 1915 - 1920 (2010/11/18)
The enzymatic resolutions of two racemic ethyl hydroxyalkane(P-phenyl) phosphinates were performed by both esterification and hydrolysis approaches. The first reaction was performed in anhydrous diisopropyl ether with triethylamine or pyridine as additive
