6033-85-8

Basic information

• Product Name: N-(4-(CARBAMOYLMETHOXY)PHENYL)ETHANAMIDE
• Synonyms: N-(4-(CARBAMOYLMETHOXY)PHENYL)ETHANAMIDE
• CAS NO: 6033-85-8
• Molecular Formula: C₁₀H₁₂N₂O₃
• Molecular Weight: 208.21
• Mol File: 6033-85-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(4-(CARBAMOYLMETHOXY)PHENYL)ETHANAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-(CARBAMOYLMETHOXY)PHENYL)ETHANAMIDE(6033-85-8)
• EPA Substance Registry System: N-(4-(CARBAMOYLMETHOXY)PHENYL)ETHANAMIDE(6033-85-8)

Safety Data

• Hazardous Substances Data: 6033-85-8(Hazardous Substances Data)

Upstream product

• 1798-11-4 4-nitrophenoxyacetic acid 
• 7732-18-5 water 
• 103-90-2 4-acetaminophenol 
• 79-07-2 Chloroacetamide 
• 63218-14-4 4-nitrophenoxyacetamide 
• 108-24-7 acetic anhydride 
• 64-17-5 ethanol 

Relevant articles and documents

Synthesis and biological evaluation of 2-Phenoxyacetamide analogues, a novel class of potent and selective monoamine oxidase inhibitors

Monoamine oxidases (EC 1.4.3.4; MAOs), a family of FAD-containing enzymes, is an important target for antidepressant drugs. In this paper, a series of 2-phenoxyacetamide analogues were synthesized, and their inhibitory potency towards monoamine oxidases A (MAO-A) and B (MAO-B) were evaluated using enzyme and cancer cell lysate. 2-(4-Methoxyphenoxy)acetamide (compound 12) (SI = 245) and (2-(4-((prop-2- ynylimino)methyl)phenoxy)acetamide (compound 21) (IC50MAO-A = 0.018 μM, IC50MAO-B = 0.07 μM) were successfully identified as the most specific MAO-A inhibitor, and the most potent MAO-A/-B inhibitor, respectively. The inhibitory activities of these two compounds in living cells were also further evaluated utilizing HepG2 and SHSY-5Y cell lysates.