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N-(4-(Carbamoylmethoxy)phenyl)ethanamide is a chemical compound with the molecular formula C10H12N2O3. It is an amide derivative, characterized by the presence of a carbamoyl group (-CO-NH2) attached to a methoxy group (-OCH3) on a phenyl ring, which is further connected to an ethanamide group (-CH2-CH2-CONH2). N-(4-(CARBAMOYLMETHOXY)PHENYL)ETHANAMIDE is known for its potential applications in pharmaceuticals and as a building block in the synthesis of various organic compounds. Its structure allows for the formation of hydrogen bonds and other interactions, which can be exploited in drug design and chemical reactions.

6033-85-8

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6033-85-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6033-85-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,0,3 and 3 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6033-85:
(6*6)+(5*0)+(4*3)+(3*3)+(2*8)+(1*5)=78
78 % 10 = 8
So 6033-85-8 is a valid CAS Registry Number.

6033-85-8Downstream Products

6033-85-8Relevant academic research and scientific papers

Synthesis and biological evaluation of 2-Phenoxyacetamide analogues, a novel class of potent and selective monoamine oxidase inhibitors

Shen, Wei,Yu, Shian,Zhang, Jiaming,Jia, Weizheng,Zhu, Qing

, p. 18620 - 18631 (2015/01/08)

Monoamine oxidases (EC 1.4.3.4; MAOs), a family of FAD-containing enzymes, is an important target for antidepressant drugs. In this paper, a series of 2-phenoxyacetamide analogues were synthesized, and their inhibitory potency towards monoamine oxidases A (MAO-A) and B (MAO-B) were evaluated using enzyme and cancer cell lysate. 2-(4-Methoxyphenoxy)acetamide (compound 12) (SI = 245) and (2-(4-((prop-2- ynylimino)methyl)phenoxy)acetamide (compound 21) (IC50MAO-A = 0.018 μM, IC50MAO-B = 0.07 μM) were successfully identified as the most specific MAO-A inhibitor, and the most potent MAO-A/-B inhibitor, respectively. The inhibitory activities of these two compounds in living cells were also further evaluated utilizing HepG2 and SHSY-5Y cell lysates.

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