60355-81-9

Upstream product

• 16619-14-0 2-phenyl-2,3-dihydro-1H-quinolin-4-one 
• 108-24-7 acetic anhydride 
• 16619-52-6 1-(2-acetylaminophenyl)-3-phenyl-2-propen-1-one 
• 78396-00-6 2-aminochalcone 
• 577-59-3 2-acetylnitrobenzene 
• 155694-75-0 1-N-acetyl-4-keto-2-phenyl-1-(phenylseleno)-1,2,3,4-tetrahydroquinoline 
• 100-52-7 benzaldehyde 
• 16619-38-8 2'-nitro-chalcone 

Downstream Products

• 80-48-8 methyl p-toluene sulfonate 
• 1203590-65-1 1-acetyl-2-phenyl-2,3-dihydroquinolin-4(1H)-one 
• 1203590-77-5 C₂₀H₁₉NO₂ 
• 1203590-88-8 C₂₀H₁₉NO₂ 
• 1309856-79-8 C₂₀H₁₉NO₂ 
• 22680-62-2 4-methoxy-2-phenyl-quinoline 

Relevant academic research and scientific papers

ZnCl2-catalyzed intramolecular cyclization reaction of 2-aminochalcones using polymer-supported selenium reagent: Synthesis of 2-phenyl-4-quinolones and 2-phenyl-2,3-dihydroquinolin-4(1 H)-one

A new and efficient method for the synthesis of 2-phenyl-4-quinolones and 2-phenyl-2,3-dihydroquinolin-4(1H)-ones is described. The reaction involves ZnCl2-mediated polystyrene-supported selenium-induced intramolecular cyclization of 2-amino-chalcones and subsequent traceless or functionalizing cleavage of selenium linker. Georg Thieme Verlag Stuttgart - New York.

Kinetic resolution of 2,3-dihydro-2-substituted 4-quinolones by palladium-catalyzed asymmetric allylic alkylation

(Chemical Equation Presented) The kinetic resolution of a carbon nucleophile is realized for the first time via Pd-catalyzed asymmetric allylic alkylation with "unstabilized" ketone enolates as the nucleophile, providing both allylated 2,3-disubstituted 2

Thallium(III) nitrate mediated ring contraction of 2-aryl-1,2,3,4- tetrahydro-4-quinolones: Stereoselective synthesis of trans methyl 2-aryl-2,3-dihydroindol-3-carboxylates

The ring contraction of N-acetyl-2-aryl-1,2,3,4-tetrahydro-4-quinolones 1a-d with thallium(III) nitrate in trimethyl orthoformate afforded stereoselectively trans methyl N-acetyl-2-aryl-2,3-dihydroindol-3-carboxylates 5a-d by oxidative rearrangement of ar

Synthesis of Isocoumarin, 1-Isoquinolone and 4(1H)-Quinolone Derivatives via Seleno-intermediates

The reaction of 2-styrylbenzoic acid 2 with N-phenylselenosuccinimide (N-PPS) affords 3-phenyl-iso-coumarin derivatives 3 and 3,4-dihydro-3-phenyl-4-(phenylseleno)isocoumarins 4 via selenolactonization.The reaction of 2-styrylbenzamides 5 and 1-(2-aminoph

The Chemistry of 2'-Amino Analogues of 2'-Hydroxychalcone and Its Derivatives

The cyclization of 2'-aminochalcone (2a) and its side-chain additives has been studied for the development of syntheses of 2-aryl-4-quinolones. 2a and its 2'-acetamido 2b and 2'-benzenesulfonamido 2c derivatives underwent acid- or base-catalyzed cyclization to 1,2,3,4-tetrahydro-4-quinolones.The α,β-dibromides of 2b and 2c cyclized to cis-3-bromo-4-quinolones as did the corresponding α-bromochalcones and the α-bromo-β-methoxy additive of 2c. 2'-Acetamido-α-bromochalcone was cyclized by acid to 1,4-dihydro-2-phenyl-4-quinolone. 2'-Aminochalcone formed a stableepoxide which, with acid, gave cis-3-hydroxy-1,2,3,4-tetrahydro-3-phenyl-4-quinolone. 2'-Aminochalcones 2a-c and their additives, such as dibromide and epoxide, are useful, readily available precursors of various 2-aryl-4-quinolones.