60419-23-0

Basic information

• Product Name: (R)-(-)-1-(2-Pyrrolidinylmethyl)pyrrolidine
• Synonyms: (R)-(-)-1-(2-PYRROLIDINYLMETHYL)PYRROLIDINE;(R)-(-)-1-(2-PYRROLIDINYLMETHYL)PYRROLIDINE 98%;(R)-(-)-1-(2-Pyrrolidinylmethyl)pyrrolidine98%;(R)-1-(Pyrrolidin-2-ylMethyl)pyrrolidine;(R)-1-(2-Pyrrolidinylmethyl)pyrrolidine dihydrochloride;Pyrrolidine, 1-[(2R)-2-pyrrolidinylmethyl]-;(2R)-2-(1-Pyrrolidinylmethyl)pyrrolidine;(R)-2-(Pyrrolidin-1-ylmethyl)pyrrolidine 2HCl
• CAS NO: 60419-23-0
• Molecular Formula: C₉H₁₈N₂
• Molecular Weight: 154.25
• Mol File: 60419-23-0.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 265.8 °C at 760 mmHg
• Flash Point: 87.8 °C
• Appearance: /
• Density: 0.975 g/cm³
• Vapor Pressure: 0.00898mmHg at 25°C
• Refractive Index: 1.4850 to 1.4890
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 10.91±0.10(Predicted)
• CAS DataBase Reference: (R)-(-)-1-(2-Pyrrolidinylmethyl)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(-)-1-(2-Pyrrolidinylmethyl)pyrrolidine(60419-23-0)
• EPA Substance Registry System: (R)-(-)-1-(2-Pyrrolidinylmethyl)pyrrolidine(60419-23-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 60419-23-0(Hazardous Substances Data)

Usage

General Description

"(R)-(-)-1-(2-Pyrrolidinylmethyl)pyrrolidine" is a synthetic compound that belongs to the family of Pyrrolidines. Pyrrolidines are organic compounds that contain a pyrrolidine moiety, which is a five-membered saturated ring with four carbon atoms and one nitrogen atom. This specific chemical, also known as Pyrrolidinium, 1-[(R)-1-(pyrrolidin-1-yl)ethyl]-, is used in various fields of research due to its ability to act as a ligand or catalyst. Its R-(-) configuration indicates that the structure of the molecule is chiral, meaning it cannot be superimposed onto its mirror image, which enriches its potential for various applications in biochemistry or medicinal chemistry.

InChI:InChI=1/C9H18N2/c1-2-7-11(6-1)8-9-4-3-5-10-9/h9-10H,1-8H2/p+2/t9-/m1/s1

Upstream product

• 128510-88-3 tert-butyl (R)-2-(4-methylbenzenesulfonyloxymethyl)pyrrolidine-1-carboxylate 
• 59378-81-3 1-(tert-butoxycarbonyl)prolin-2R-ol 
• 68832-13-3 D-prolinol 
• 147-85-3 L-proline 
• 344-25-2 D-Prolin 
• 144243-44-7 (R)-(+)-1-pyrrolidine 
• 37784-17-1 N-(tert-butoxycarbonyl)-D-proline 
• 1192-63-8 1-pyrrolidinecarbonyl chloride 
• 4042-36-8 D-pyrrolidone-5-carboxylic acid 
• 110958-18-4 (R)-5-[(pyrrolidin-1-yl)carbonyl]pyrrolidin-2-one 
• 144243-44-7 tert-butyl (S)-2-(pyrrolidine-1-carbonyl)pyrrolidine-1-carboxylate 
• 144243-45-8 (R)-(+)-1-prolinamidopyrrolidine 

Downstream Products

• 575467-47-9 (E)-1-((R)-2-Pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-3-(4-trifluoromethyl-phenyl)-propenone 
• 914298-88-7 (R)-(5-chloro-2,4-bis(methoxymethoxy)phenyl)(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)methanone 
• 1401301-06-1 (R)-2-(1-isopropyl-1H-1,2,4-triazol-5-yl)-9-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine 
• 1550175-01-3 4-((5-methyl-4-(4-(trifluoromethoxy)phenyl)pyrimidin-2-yl)amino)-N-(2-methyl-5-((2-(1-pyrrolidinylmethyl)-1-pyrrolidinyl)methyl)phenyl)benzamide 
• 1227075-57-1 (R)-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanone 
• 756520-44-2 (R)-(4-(6-amino-5-hydroxypyridin-3-yl)phenyl)(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)methanone 
• 756520-43-1 (R)-(4-(5-benzyloxy-6-aminopyridin-3-yl)phenyl)(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)methanone 

Relevant articles and documents

NOVEL BETULINIC SUBSTITUTED AMIDE DERIVATIVES AS HIV INHIBITORS

The present invention relates to novel betulinic substituted amide compounds of formula (I); and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, X, Y, Z1, Z2, Z3 and are Formula (II) as defined herein. The invention novel betulinic substituted amide derivatives, related compounds, and pharmaceutical compositions useful for the therapeutic treatment of viral diseases and particularly HIV mediated diseases.

ENANTIOMERICALLY PURE AMINOHETEROARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS

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Sulfonamide lactam inhibitors of FXa and method

Sulfonamide lactams of the following formula wherein X, R1, R2, R3, R4, R4a, R5, R5a, R6, R6a, R7 and R8 are as described herein, are provided which inhibitors of Factor Xa and are useful as anticoagulants in the treatment of cardiovascular diseases associated with thromboses.