60451-91-4

Upstream product

• 78555-63-2 3-(2-phenyl-1,3-dithian-2-yl)-1,2-benzisoxazole 
• 31879-18-2 phenylglyoxylonitrile oxide 
• 118-92-3 anthranilic acid 
• 49660-38-0 2-chlorobenzonitrile oxide 
• 53178-41-9 2-lithio-2-phenyl-1,3-dithiane 
• 78555-77-8 2-phenyl-1,3-dithian-2-yl o-chlorophenylketoxime 
• 5425-44-5 2-Phenyl-[1,3]dithiane 
• 74954-96-4 (2-Chloro-phenyl)-(2-phenyl-[1,3]dithian-2-yl)-methanone oxime 
• 74955-20-7 (2-Chloro-phenyl)-(2-phenyl-[1,3]dithian-2-yl)-methanone oxime 
• 29568-74-9 2-chloro-N-hydroxybenzimidoyl chloride 
• 1082682-56-1 methyl benzo[d]isoxazole-3-carboxylate 
• 100-58-3 phenylmagnesium bromide 

Downstream Products

• 611-20-1 salicylonitrile 
• 93-89-0 benzoic acid ethyl ester 

Relevant academic research and scientific papers

Reactivity of the ester group attached isoxazoline, benzisoxazole, and isoxazole: A facial preparation of 3-acyl-substituted these heterocycles

A facile preparation of 3-acyl-substituted isoxazolines, benzisoxazoles, and isoxazoles from the corresponding 3-carboxylate esters is described. The process, involving reaction of the ester derivative of 3-carboxylic acid substituted heterocycles with Gr

Synthesis of 3-Acyl-1,2-benzisoxazoles

A convenient method for the synthesis of 3-acyl-1,2-benzisoxazoles, which are unstable toward bases, is described.Base-catalyzed cyclization of 2-alkyl- and aryl-1,3-dithian-2-yl o-chlorophenylketoximes 4a-l gave 3-(2-alkyl- and aryl-1,3-dithian-2-yl)-1,2-benzisoxazoles 8a-l, which were converted into the corresponding 3-acyl-1,2-benzisoxazoles 1a-l.

REACTIONS OF NITRILE OXIDES WITH 2-LITHIO-1,3-DITHIANES, SYNTHESIS OF α-DIKETONES

Nitril oxides (2) were treated with 2-lithio-1,3-dithianes (4) to give in good yields masked ketoximes (5), new synthetic tools for α-diketones.