606-19-9

Usage

Uses

Used in Chemical Synthesis:
2-Hydroxyisophthalic acid is used as a key intermediate in the synthesis of various specialty chemicals and polymers. Its presence of both carboxylic acid and hydroxyl functional groups allows for versatile chemical reactions, making it a valuable building block for the production of high-performance materials.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 2-Hydroxyisophthalic acid is utilized as a starting material for the development of novel drug candidates. Its ability to form hydrogen bonds and participate in various chemical reactions enables the creation of new compounds with potential therapeutic applications.
Used in Coatings and Adhesives:
2-Hydroxyisophthalic acid is employed as a cross-linking agent in the formulation of coatings and adhesives. Its reactive functional groups facilitate the formation of strong bonds between polymer chains, resulting in improved mechanical properties and durability of the final products.
Used in Textile Industry:
In the textile industry, 2-Hydroxyisophthalic acid is used as a component in the production of dyestuffs and finishing agents. Its chemical reactivity allows for the attachment of various functional groups, which can enhance the colorfastness, water resistance, and other properties of textiles.
Used in Agriculture:
2-Hydroxyisophthalic acid is utilized in the development of agrochemicals, such as herbicides and pesticides. Its chemical properties enable the design of compounds that can effectively control the growth of unwanted plants and pests, thereby improving crop yields and quality.

InChI:InChI=1/C8H6O5/c9-6-4(7(10)11)2-1-3-5(6)8(12)13/h1-3,9H,(H,10,11)(H,12,13)

Upstream product

• 2902-65-0 2-iodoyl-1,3-benzenedicarboxylic acid 
• 83-40-9 3-methylsalicylic acid 
• 1951-38-8 2-methoxyisophthalic acid 
• 101670-85-3 methyl 3-carboxysalicylate 
• 56-23-5 tetrachloromethane 
• 69-72-7 salicylic acid 
• 39055-80-6 3-trifluoromethyl-salicylonitrile 
• 64-17-5 ethanol 
• 610-04-8 3-formylsalicylic acid 
• 3328-69-6 2-hydroxy-isophthalaldehyde 
• 576-22-7 2-Bromo-m-xylene 
• 7647-01-0 hydrogenchloride 
• 1071072-68-8 5-formyl-2-hydroxy-isophthalic acid 
• 855641-74-6 5-formyl-4-hydroxy-isophthalic acid 

Downstream Products

• 36669-06-4 dimethyl 2-hydroxyisophthalate 
• 1071072-68-8 5-formyl-2-hydroxy-isophthalic acid 
• 1951-38-8 2-methoxyisophthalic acid 
• 88554-09-0 2-hydroxy-isophthalic acid diphenyl ester 
• 36727-13-6 2-methoxy-1,3-benzenedicarboxylic acid dimethyl ester 
• 124-38-9 carbon dioxide 
• 69-72-7 salicylic acid 
• 258331-08-7 di-tert-butyl 2-hydroxyisophthalate 
• 107020-24-6 Potassium; 2-methoxy-3-methoxycarbonyl-benzoate 
• 101670-85-3 methyl 3-carboxysalicylate 
• 107020-28-0 2-methoxy-3-methoxycarbonylbenzoyl chloride 
• 96400-54-3 naucleficine 
• 107020-25-7 2,3,4,9-tetrahydro-2-(2-methoxy-3-methoxycarbonylbenzoyl)-1-methylene-1H-pyrido<3,4-b>indole 
• 67294-53-5 2-hydroxy-5-nitrobenzene-1,3-dicarboxylic acid 

Relevant academic research and scientific papers

Designer ligands for beryllium

We report the rational design of ligands that selectively bind beryllium. We selected two ligands to design Be based on binding polynulear species with a Be-O-Be motif: 2-hydroxyisophthalic acid (HIPA) and 2,3-dihydroxybenzoic acid (DHBA). All previous wo

Complexes and Ligands

The present application provides ligands and fluorescent or luminescent complexes comprising these ligands.

High-relaxivity Gd(III)-hemicryptophane complex

The polytopic hemicryptophane cage HC1 combining a cyclotriveratrylene (CTV) unit and a tris(2-aminoethyl)amine (tren) moiety connected by three 2-hydroxyisophthalamide linkers was synthesized in 12 steps. The resulting highly functionalized covalent host

Slow Formation of Pseudorotaxanes in Water

The synthesis of two water-soluble oligophenylene-ethynylene (OPE)-rods with substituted iso- and terephthalate end groups is presented. Both undergo slow association with a Diederich-type cyclophane in aqueous solution. Formation of [2]pseudorotaxanes oc

Tenacic Acids: A New Class of Tenacious Binders to Metal Oxide Surfaces

The backbone of 2-hydroxyisophthalic acid was identified as a potential metal oxide anchor because of the perfect alignment of all three of its donor groups for binding to inorganic surfaces. It can therefore be used in the design of organic linkers for m

Functionalized hydrazide macrocycle ion channels showing pH-sensitive ion selectivities

Transmembrane channels formed by functionalized hydrazide macrocycles are reported. The different pH values of buffer solutions have a significant effect on the K+/Cl- selectivity of the macrocycles. This unique transport behavior is

One-pot formation of hydrazide macrocycles with modified cavities: An example of pH-sensitive unimolecular cation channels

A series of pH-sensitive, cation-selective hydrazide macrocyclic channels have been synthesized. The macrocyclic channels bear multiple carboxyls in the inner cavity, which have a significant impact on their membrane-incorporation ability and NH4/su

2-HYDROXYISOPHTHALIC ACID AND ITS DERIVATIVES: METHODS OF MAKING AND APPLICATIONS

Substituted derivatives of 2-hydroxyisophthalic acid are provided, as well as new synthetic routes for making 2-hydroxyisophthalic acid and the substituted derivatives. Potential uses of the derivatives in a variety of applications are also provided.

Ultrabright Lanthanide Nanoparticles

Tb-doped La0.9Tb0.1F3 nanoparticles were prepared by a simple and reproducible microwave-assisted synthetic protocol in water. The nanoparticles were characterized by XRD, TEM, dynamic light scattering and inductively coup

Siderophore inspired tetra- and octadentate antenna ligands for luminescent Eu(III) and Tb(III) complexes

Following the success of the siderophore-inspired 1,2-hydroxypyridonate (HOPO) and 2-hydroxisophthalamide (IAM) chromophores in Eu(III) and Tb(III) luminescence, we designed three new ligands bearing both chromophores. Syntheses of the octadentate ligands