60611-62-3

Upstream product

• 74245-43-5 5-(4-Chloro-benzyl)-2-cyclopropyl-pyridine 
• 56260-49-2 2-cyclopropyl-5-cyclopropylcarbonylpyridine 
• 108-90-7 chlorobenzene 
• 10400-19-8 3-pyridinecarbonyl chloride 
• 14774-78-8 4-chlorophenyl lithium 
• 82465-58-5 5-(4-Chlorbenzoyl)-2-pyridincarboxamid 
• 14548-44-8 3-(4-chlorobenzoyl)pyridine 

Relevant academic research and scientific papers

A New Simple Synthesis of Fusaric Acid and Other 5-Alkyl-2-pyridinecarboxylic Acids

Carboxamido groups are introduced into the 6-position of 3-acylpyridines with high regioselectivity via Minisci reaction with formamides, Fe(II) sulfate and tert-butyl hydroperoxide.The isolation procedure is considerably improved by the addition of citric acid for complexation of the Fe ions.Fusaric acid and other 5-alkyl-2-pyridine carboxylic acids are obtained by a following Wolff-Kishner reaction in 20-75percent overall yield.

SYNTHESIS OF 5-(SUBSTITUTED ALKYL)PICOLINIC ACIDS, THE DOPAMINE β-HYDROXYLASE INHIBITORS. III

Several 5-alkylpicolinic acids, dopamine β-hydroxylase inhibitors were synthesized from 2-cyclopropyl-5-cyclopropylcarbonylpyridine (I) as a suitable starting material.