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60637-33-4

2-Chloro-pyrazolo[1,5-a]pyridine is a heterocyclic chemical compound characterized by the molecular formula C7H5ClN2. It features a chloro group attached to a fused pyrazole and pyridine rings, which endows it with unique structural and potential biological properties. 2-Chloro-pyrazolo[1,5-a]pyridine is recognized for its role as a versatile building block in the synthesis of pharmaceuticals and agrochemicals, as well as its utility in research for preparing other organic compounds. Its distinctive structure positions 2-Chloro-pyrazolo[1,5-a]pyridine as a promising candidate in medicinal chemistry and drug discovery. However, due to potential hazards and risks, careful handling and storage are imperative.

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  • 60637-33-4 Structure

  • Basic information

    1. Product Name: 2-CHLORO-PYRAZOLO[1,5-A]PYRIDINE
    2. Synonyms: 2-CHLORO-PYRAZOLO[1,5-A]PYRIDINE;2-chloroH-pyrazolo[1,5-a]pyridine
    3. CAS NO:60637-33-4
    4. Molecular Formula: C7H5ClN2
    5. Molecular Weight: 152.58
    6. EINECS: N/A
    7. Product Categories: Building Blocks;Pyrazolo[x,x-y]pyridine;Heterocycle-Pyridine series
    8. Mol File: 60637-33-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.35 g/cm3
    6. Refractive Index: 1.653
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-CHLORO-PYRAZOLO[1,5-A]PYRIDINE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-CHLORO-PYRAZOLO[1,5-A]PYRIDINE(60637-33-4)
    11. EPA Substance Registry System: 2-CHLORO-PYRAZOLO[1,5-A]PYRIDINE(60637-33-4)

  • Safety Data

    1. Hazard Codes: Xn
    2. Statements: 22
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 60637-33-4(Hazardous Substances Data)

60637-33-4 Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
2-Chloro-pyrazolo[1,5-a]pyridine is utilized as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its unique structure allows for the development of new compounds with potential therapeutic and pesticidal properties, contributing to the advancement of these industries.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 2-Chloro-pyrazolo[1,5-a]pyridine serves as a valuable reagent for the preparation of novel organic compounds with potential biological activity. Its incorporation into drug discovery pipelines facilitates the exploration of new chemical entities that may address unmet medical needs.
Used in Chemical Research and Development:
2-Chloro-pyrazolo[1,5-a]pyridine is employed as a research reagent for the synthesis and study of other organic compounds. Its unique structural features make it an attractive candidate for investigating new chemical reactions and exploring the properties of newly synthesized compounds, thereby expanding the scope of chemical research and development.

Check Digit Verification of cas no

The CAS Registry Mumber 60637-33-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,6,3 and 7 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 60637-33:
(7*6)+(6*0)+(5*6)+(4*3)+(3*7)+(2*3)+(1*3)=114
114 % 10 = 4
So 60637-33-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H5ClN2/c8-7-5-6-3-1-2-4-10(6)9-7/h1-5H

60637-33-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Chloropyrazolo[1,5-a]pyridine

1.2 Other means of identification

Product number -
Other names 2-chloropyrazolo[1,5-a]pyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:60637-33-4 SDS

60637-33-4Relevant articles and documents

Synthesis of 2-Arylpyrazolo[1,5- a ]pyridines by Suzuki-Miyaura Cross-Coupling Reaction

Umei, Kentaro,Nishigaya, Yosuke,Kamiya, Megumi,Kohno, Yasushi,Seto, Shigeki

, p. 3221 - 3230 (2015/10/19)

Convenient access to a variety of 2-arylated pyrazolo[1,5-a]pyridine via pyrazolo[1,5-a]pyridine-2-yl triflate using the Suzuki-MiyauraA AA cross-coupling reaction is described. Fifteen 2-arylpyrazolo[1,5-a]pyridine derivatives were synthesized in 52-95% yields.

PYRAZOLOPYRIDYL COMPOUNDS AS ALDOSTERONE SYNTHASE INHIBITORS

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Page/Page column 54; 55, (2013/04/10)

This invention relates to pyrazolopyridyl compounds of the structural formula: [Formula should be inserted here] or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone s

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