607-90-9

Basic information

• Product Name: SALICYLIC ACID N-PROPYL ESTER
• Synonyms: 2-HYDROXYBENZOIC ACID N-PROPYL ESTER;2-hydroxy-benzoicacipropylester;Benzoic acid, 2-hydroxy-, propyl ester;Propyl o-hydroxybenzoate;Salicylic acid, propyl ester;SALICYLIC ACID N-PROPYL ESTER;N-PROPYL-O-HYDROXYBENZOATE;N-PROPYL SALICYLATE
• CAS NO: 607-90-9
• Molecular Formula: C₁₀H₁₂O₃
• Molecular Weight: 180.2
• EINECS: 210-145-3
• Product Categories: Aromatic Esters
• Mol File: 607-90-9.mol
• Article Data: 11

Chemical Properties

• Melting Point: 97°C
• Boiling Point: 246 °C
• Flash Point: 100.5 °C
• Appearance: /
• Density: 1.10
• Vapor Pressure: 0.0266mmHg at 25°C
• Refractive Index: 1.5140 to 1.5170
• PKA: 8.16±0.30(Predicted)
• CAS DataBase Reference: SALICYLIC ACID N-PROPYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: SALICYLIC ACID N-PROPYL ESTER(607-90-9)
• EPA Substance Registry System: SALICYLIC ACID N-PROPYL ESTER(607-90-9)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 3
• Hazardous Substances Data: 607-90-9(Hazardous Substances Data)

Usage

General Description

SALICYLIC ACID N-PROPYL ESTER is a chemical compound that is a propyl ester derivative of salicylic acid. It is often used in the formulation of skincare products, particularly in acne treatment products, due to its anti-inflammatory, exfoliating, and antimicrobial properties. SALICYLIC ACID N-PROPYL ESTER works by penetrating the skin and exfoliating the top layer, which helps to unclog pores and prevent acne. It also has antifungal and antibacterial properties, making it effective in treating various skin conditions. Additionally, SALICYLIC ACID N-PROPYL ESTER may also be used in pharmaceuticals and industrial applications due to its versatile properties.

InChI:InChI=1/C10H12O3/c1-2-7-13-10(12)8-5-3-4-6-9(8)11/h3-6,11H,2,7H2,1H3

Upstream product

• 71-23-8 propan-1-ol 
• 56-23-5 tetrachloromethane 
• 108-95-2 phenol 
• 540-54-5 1-Chloropropane 
• 69-72-7 salicylic acid 
• 119-36-8 methyl salicylate 
• 627-13-4 propyl nitrate 
• 118-93-4 o-hydroxyacetophenone 
• 6640-69-3 1-(2-hydroxyphenyl)-2-methylpropan-1-one 
• 610-99-1 1-(2-Hydroxy-phenyl)-propan-1-on 
• 1809-21-8 di-n-propyl phosphonate 

Downstream Products

• 87188-65-6 2-hydroxy-5-isopropyl-benzoic acid methyl ester 
• 52159-64-5 3-Isopropylsalicylic acid methyl ester 
• 52040-40-1 2-hydroxy-3,5-dinitro-benzoic acid propyl ester 
• 119-36-8 methyl salicylate 
• 124103-75-9 2-(tetra-O-acetyl-β-D-glucopyranosyloxy)-benzoic acid propyl ester 
• 60310-03-4 2-acetoxy-benzoic acid propyl ester 

Relevant articles and documents

Synthesis of Hydroxybenzoic Acids and Their Esters by Reaction of Phenols with Carbon Tetrachloride and Alcohols in the Presence of Iron Catalysts

Alkyl esters of hydroxy-, methoxy-, and ethoxybenzoic and cresotic acids have been synthesized by reaction of phenols, anisole, phenetole, and cresols with carbon tetrachloride and alcohols in the presence of iron catalysts.

Efficient microwave-assisted esterification reaction employing methanesulfonic acid supported on alumina as catalyst

A rapid and efficient protocol assisted by microwave irradiation for the synthesis of esters using methanesulfonic acid (CH3SO3H) supported on Al2O3 (AMA) as catalyst and free of solvent is described. The products were obtained in good yields and purity, with reduced reaction time, and the process is simple and environmentally benign. Copyright

SO3H-functionalized Bronsted acidic ionic liquids as efficient catalysts for the synthesis of isoamyl salicylate

Six Bronsted acidic ionic liquids (BAILs) composed of [HSO 4] were prepared, characterized, and used as catalysts of low dosage in the synthesis of isoamyl salicylate. The effects of various parameters such as the kind of BAILs, temperature, catalyst loading, and molar ratio of the reactants on the conversion of salicylic acid were also examined in detail. The results suggested that the catalytic performances of BAILs were of close relevance to their Hammett acidities. The SO3H-functionalized BAILs 1-(4-sulfonic acid) butyl-3-methylimidazolium hydrogen sulfate ([BSmim][HSO 4]) and N-(4-sulfonic acid) butyl triethylammonium hydrogen sulfate ([BSEt3N][HSO4]) of strong acidities exhibited excellently catalytic activities and selectivities in the esterification of salicylic acid with isoamyl alcohol. The fully optimized geometries of [BSmim][HSO4] and [BSEt3N][HSO4] further manifest that their strong acidities are derived from the strong interactions between the anion with the sulfonic acid group. In addition, it was found that [BSmim][HSO4] could be also recovered easily and used repetitively at least six times without obvious decline in activity and quantity.